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Comment
. 2021 Jan;42(2):E2-E3.
doi: 10.3174/ajnr.A6943. Epub 2020 Dec 3.

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M F V V Aragão  1   2 , M C Leal  1   3 , T M Fonseca  3 , O Q Cartaxo Filho  3 , M M Valença  1
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M F V V Aragão et al. AJNR Am J Neuroradiol. 2021 Jan.
No abstract available

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Figures

FIGURE.
FIGURE.
A woman in her 60s with confirmed COVID-19 for which MR imaging shows a hyperintense lesion on a coronal reconstruction of 3D-FLAIR (A, arrow) and also on pre- (B, arrow) and postcontrast SPGR T1WI (C, arrow). This is suggestive of a component of probably methemoglobin in this left olfactory bulb lesion, which seems to be a little larger and asymmetric compared with the apparently normal right olfactory bulb. This asymmetry is better seen on FLAIR. On FLAIR (A, short arrow), there is also a small round hyperintense lesion in the subcortical white matter in the left frontal lobe, which is hypointense on T1WI (B, short arrow) and does not enhance on postcontrast T1WI (C, short arrow), being no specific lesion area probably corresponding to gliosis. This patient also had some areas of brain parenchymal bleeding and microbleeding, and had around 50% of the bilateral pulmonary parenchyma compromised with typical COVID-19 lesions on chest CT, not shown in this figure.
See this image and copyright information in PMC

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References

    1. Aragão MF, Leal MC, Cartaxo Filho OQ, et al. . Anosmia in COVID-19 associated with injury to the olfactory bulbs evident on MRI. AJNR Am J Neuroradiol 2020;41:1703–06 10.3174/ajnr.A6675 - DOI - PMC - PubMed
    1. Hong JH, Lee HY, Kang YH, et al. . Improvement of fat suppression and artifact reduction using IDEAL technique in head and neck MRI at 3T. Investig Magn Reson Imaging 2016;20:44–52 10.13104/imri.2016.20.1.44 - DOI
    1. Lascano AM, Hummel T, Lacroix JS, et al. . Spatio-temporal dynamics of olfactory processing in the human brain: an event-related source imaging study. Neuroscience 2010;167:700–08 10.1016/j.neuroscience.2010.02.013 - DOI - PubMed
    1. Laurendon T, Radulesco T, Mugnier J, et al. . Bilateral transient olfactory bulb edema during COVID-19-related anosmia. Neurology 2020;95:224–225 10.1212/WNL.0000000000009850 - DOI - PubMed
    1. Chetrit A, Lechien JR, Ammar A, et al. . Magnetic resonance imaging of COVID-19 anosmic patients reveals abnormalities of the olfactory bulb: preliminary prospective study. The Journal of Infection 2020. 10.1016/j.jinf.2020.07.028 - DOI - PMC - PubMed