Persistent symptoms 1.5-6 months after COVID-19 in non-hospitalised subjects: a population-based cohort study
- PMID: 33273028
- PMCID: PMC7716295
- DOI: 10.1136/thoraxjnl-2020-216377
Persistent symptoms 1.5-6 months after COVID-19 in non-hospitalised subjects: a population-based cohort study
Abstract
This study assessed symptoms and their determinants 1.5-6 months after symptom onset in non-hospitalised subjects with confirmed COVID-19 until 1 June 2020, in a geographically defined area. We invited 938 subjects; 451 (48%) responded. They reported less symptoms after 1.5-6 months than during COVID-19; median (IQR) 0 (0-2) versus 8 (6-11), respectively (p<0.001); 53% of women and 67% of men were symptom free, while 16% reported dyspnoea, 12% loss/disturbance of smell, and 10% loss/disturbance of taste. In multivariable analysis, having persistent symptoms was associated with the number of comorbidities and number of symptoms during the acute COVID-19 phase.
Keywords: clinical epidemiology; pneumonia; viral infection.
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Conflict of interest statement
Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf. WG reports grants and personal fees from Novartis, grants and personal fees from Amgen, grants from Bayer, grants from BMS, grants from Pfizer, personal fees from MSD, outside the submitted work. The other authors declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work.
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