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. 2020;82(6):50-54.
doi: 10.17116/patol20208206150.

[Tropical malaria with a fatal outcome]

[Article in Russian]
Affiliations

[Tropical malaria with a fatal outcome]

[Article in Russian]
A N Kovalenko et al. Arkh Patol. 2020.

Abstract

Tropical malaria is an acute infectious disease from a group of parasitic diseases transmitted by the vector-borne route. Russia registers deaths due to imported malaria. The paper gives brief information on the epidemiology, etiology, and clinical manifestations of the disease and describes the fatal outcome of cerebral tropical malaria, as well as morphological changes in organs and tissues. The K76T mutation associated with drug resistance in parasites was identified in the structure of the plasmodium gene.

Тропическая малярия — острое инфекционное заболевание из группы паразитозов, передающееся трансмиссивным путем. В России регистрируются летальные исходы завозных случаев малярии. Изложены краткие сведения, касающиеся эпидемиологии, этиологии и клинических проявлений заболевания, а также представлено наблюдение летального исхода при церебральной форме тропической малярии, описаны морфологические изменения в органах и тканях. В структуре гена плазмодия выявлена мутация K76T, ассоциированная с лекарственной резистентностью паразитов.

Keywords: Plasmodium falciparum; cerebral malaria; fatal outcome; organ damage; sequencing.

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