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Review
. 2020 Dec 4;2020(1):547-552.
doi: 10.1182/hematology.2020000140.

Women and bleeding disorders: diagnostic challenges

Affiliations
Review

Women and bleeding disorders: diagnostic challenges

Paula D James. Hematology Am Soc Hematol Educ Program. .

Abstract

Women with bleeding disorders suffer from multiple bleeding symptoms, including easy bruising, epistaxis, bleeding from minor wounds and the oral cavity, and bleeding after dental work or surgery. However, women with bleeding disorders especially suffer from gynecologic and obstetrical bleeding. These symptoms often are not recognized as abnormal, and many women are left undiagnosed and without access to appropriate medical care. Additional challenges to diagnosing women with bleeding disorders include lack of access to appropriate laboratory testing and issues around disease classification and nomenclature. Efforts have been undertaken to address these challenges, including the development and validation of bleeding assessment tools and strategies to clarify diagnostic thresholds and algorithms for von Willebrand disease (VWD) and platelet function disorders. Efforts to improve communication with the nomenclature used for hemophilia carriers are also underway.

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Conflict of interest statement

Conflict-of-interest disclosure: The author declares no competing financial interests.

Figures

None
Graphical abstract
Figure 1.
Figure 1.
Homepage of Let’s Talk Period.
Figure 2.
Figure 2.
Global reach of Let’s Talk Period.
Figure 3.
Figure 3.
Proposed nomenclature for hemophilia carriers and women and girls with hemophilia.

References

    1. Oehler MK, Rees MCP. Menorrhagia: an update. Acta Obstet Gynecol Scand. 2003;82(5):405-422. - PubMed
    1. Knol HM, Mulder AB, Bogchelman DH, Kluin-Nelemans HC, van der Zee AG, Meijer K. The prevalence of underlying bleeding disorders in patients with heavy menstrual bleeding with and without gynecologic abnormalities. Am J Obstet Gynecol. 2013;209(3):202.e1-202.e7. - PubMed
    1. Kadir RA, Economides DL, Sabin CA, Owens D, Lee CA. Frequency of inherited bleeding disorders in women with menorrhagia. Lancet. 1998;351(9101):485-489. - PubMed
    1. Edlund M, Blombäck M, von Schoultz B, Andersson O. On the value of menorrhagia as a predictor for coagulation disorders. Am J Hematol. 1996;53(4):234-238. - PubMed
    1. Kouides PA, Phatak PD, Burkart P, et al. . Gynaecological and obstetrical morbidity in women with type I von Willebrand disease: results of a patient survey. Haemophilia. 2000;6(6):643-648. - PubMed