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Comment
. 2020 Dec;184(4):1627-1629.
doi: 10.1104/pp.20.01456.

How to Make an Extraordinary Machine: SMALL ORGAN4 Regulates Ribosome Biogenesis in Plants

Eva Hellmann  1
Affiliations
Comment

How to Make an Extraordinary Machine: SMALL ORGAN4 Regulates Ribosome Biogenesis in Plants

Eva Hellmann. Plant Physiol. 2020 Dec.
No abstract available

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Figures

Figure 1.
Figure 1.
Overview of rRNA maturation and involvement of SMO4 in pre-5.8S rRNA accumulation. A, Schematic overview of the rRNA genomic arrangement and maturation adapted from Henras et al. (2008) and Palm et al. (2019). One unit of rRNA genes is organized in repeats of 5S rRNA and polycistronic 18S, 5.8S, and 25S rRNA on the DNA. Transcription leads to a 45S rRNA precursor with 5′ external transcribed spacer (5′ETS), the two separating internal transcribed spacers 1 (ITS1) and ITS2, and the noncoding 3′ transcribed spacer (3′ETS). Cleaving sites are indicated with arrowheads, and the probes used to identify different rRNA intermediates on the gel blots are indicated as gray stars. The mature rRNAs are shown below. The probe marked in the 5′ETS indicates precursors of the 18S rRNA fragment and an early intermediate containing 18S, 5.8S, and 25S rRNA. The probe marked in ITS1 indicates the same precursors plus some later stages of 18S rRNA maturation. The probe marked in ITS2 indicates precursors for 5.8S rRNA and fragments containing the 5.8S and 25S rRNA. B, Gel blot modified from figure 3B of Micol-Ponce et al. (2020). In contrast to the wild-type backgrounds Landsberg erecta (Ler) and Columbia-0 (Col-0) and the complemented smo4 mutant, the smo4 alleles and mtr4 show the accumulation of 5.8S rRNA precursors.
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References

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