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Review
. 2021 Feb 1;33(1):90-96.
doi: 10.1097/MOP.0000000000000970.

Chronic recurrent multifocal osteomyelitis: diagnosis and treatment

Fernando Moreno-Mateo  1 , Sofía Hidalgo Perea  2 , Karen Brandt Onel  3
Affiliations
Review

Chronic recurrent multifocal osteomyelitis: diagnosis and treatment

Fernando Moreno-Mateo et al. Curr Opin Pediatr. .

Abstract

Purpose of review: The aim of this article is to review recent findings regarding the diagnosis and treatment of chronic recurrent multifocal osteomyelitis (CRMO).

Recent findings: An adequate understanding of pathophysiology along with the new advances in MRI imaging make it possible to determine the extent of disease and establish early treatment. TNF-α inhibitors and bisphosphonates have shown to be a well-tolerated and efficient treatment for CRMO providing both symptomatic relief and normalization of bone morphology.

Summary: The results of recent studies suggest that a better knowledge of the genetic and molecular factors will allow early diagnosis and the development of more effective individualized treatments in the future.

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References

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