Paediatric COVID-19: Milder Presentation-A Silver Lining in Dark Cloud
- PMID: 33280024
- PMCID: PMC7798610
- DOI: 10.1093/tropej/fmaa106
Paediatric COVID-19: Milder Presentation-A Silver Lining in Dark Cloud
Abstract
Objective: To assess the clinico-epidemiological profile of paediatric patients with Corona virus disease 2019 (COVID-19) infection during the pandemic.
Methods: Clinico-epidemiological and laboratory profile of children between 1 month and 14 years were studied between 15 May and 31 July 2020, who had positive nasopharyngeal and oropharyngeal swab for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) by reverse transcriptase-polymerase chain reaction (RT-PCR).
Results: A total of 30 children with median age of 10.5 years (8 months to 14 years) were included in the present study. Sixty percent were boys. Twenty-seven (90%) belonged to an urban area and all 30 children were from a containment area. All were belonging to Kuppuswamy upper lower and lower socioeconomic class. Twenty-one (70%) were asymptomatic. All children had a positive household contact. Symptomatic children had only mild symptoms of fever, dry cough and rhinitis. All were fully vaccinated as per age. Nine (30%) had anaemia. The mean leucocyte count was 7470 ± 2427 (4300-14 100). Leucocytosis was seen in 3 (9%) children. C-reactive protein was found to be raised in only 4 (13%) children. We did not find alteration in sense of smell and taste. No mortality was reported.
Conclusion: COVID-19 in paediatric patients is usually mild. Severe acute respiratory infection is not a major manifestation of COVID 19 infection in children. All children infected by the novel Corona virus-2 in this study, have a documented household contact.
Keywords: COVID 19; SARS-CoV-2; children; clinico-epidemiological profile.
© The Author(s) [2020]. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.
Similar articles
-
Epidemiological and Clinical Characteristics of COVID-19 in Indian Children in the Initial Phase of the Pandemic.Indian Pediatr. 2020 Oct 15;57(10):914-917. doi: 10.1007/s13312-020-1994-4. Epub 2020 Jul 28. Indian Pediatr. 2020. PMID: 32729850 Free PMC article.
-
Clinical Characteristics and Viral RNA Detection in Children With Coronavirus Disease 2019 in the Republic of Korea.JAMA Pediatr. 2021 Jan 1;175(1):73-80. doi: 10.1001/jamapediatrics.2020.3988. JAMA Pediatr. 2021. PMID: 32857112 Free PMC article.
-
Clinical and epidemiological characteristics of children with SARS-CoV-2 infection: a case series in Sinaloa.Bol Med Hosp Infant Mex. 2021;78(1):18-23. doi: 10.24875/BMHIM.200002021. Bol Med Hosp Infant Mex. 2021. PMID: 33661874 English.
-
Duration of Respiratory and Gastrointestinal Viral Shedding in Children With SARS-CoV-2: A Systematic Review and Synthesis of Data.Pediatr Infect Dis J. 2020 Sep;39(9):e249-e256. doi: 10.1097/INF.0000000000002814. Pediatr Infect Dis J. 2020. PMID: 32618932
-
Clinical characteristics and diagnostic challenges of pediatric COVID-19: A systematic review and meta-analysis.J Formos Med Assoc. 2020 May;119(5):982-989. doi: 10.1016/j.jfma.2020.04.007. Epub 2020 Apr 16. J Formos Med Assoc. 2020. PMID: 32307322 Free PMC article.
Cited by
-
Taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis.Chem Senses. 2023 Jan 1;48:bjad043. doi: 10.1093/chemse/bjad043. Chem Senses. 2023. PMID: 38100383 Free PMC article.
-
Taste loss as a distinct symptom of COVID-19: A systematic review and meta-analysis.medRxiv [Preprint]. 2021 Oct 9:2021.10.09.21264771. doi: 10.1101/2021.10.09.21264771. medRxiv. 2021. Update in: Chem Senses. 2022 Jan 1;47:bjac001. doi: 10.1093/chemse/bjac001. PMID: 34671775 Free PMC article. Updated. Preprint.
-
Gender and genetic factors impacting COVID-19 severity.J Family Med Prim Care. 2021 Nov;10(11):3956-3963. doi: 10.4103/jfmpc.jfmpc_769_21. Epub 2021 Nov 29. J Family Med Prim Care. 2021. PMID: 35136752 Free PMC article. Review.
References
-
- Guidelines on Clinical Management of COVID-19. Government of India Ministry of Health & Family Welfare Directorate General of Health Services (EMR Division), pp. 3–5. https://www.mohfw.gov.in/pdf/GuidelinesonClinicalManagementofCOVID191202...18 August 2020, date last accessed).
-
- Containment and surveillance manual for supervisors in containment zones. Ministry of Health and Family Welfare, Government of India. https://www.mohfw.gov.in/pdf/ContainmentandSurveillanceManualforSupervis... (20 September 2020, date last accessed).
-
- Demaeyer EM, Dallman P, Gurney JM, et al. Preventing and Controlling Iron Deficiency Anemia through Primary Health Care: A Guide for Health Administrators and Programme Managers. World Health Organization, 1989; pp. 8–9. https://www.who.int/nutrition/publications/micronutrients/anaemia_iron_d... (18 August 2020, date last accessed).
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Research Materials
Miscellaneous