Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Nov 17;12(2):8396.
doi: 10.4081/hr.2020.8396. eCollection 2020 Nov 16.

Surgery results in low relapse and progression rates in extramedullary plasmacytoma of the head and neck: A case cohort and review of the literature

Matevz Skerget  1   2 , Tadej Dovsak  1   2 , Gregor Kos  3 , Samo Zver  1   2
Affiliations

Surgery results in low relapse and progression rates in extramedullary plasmacytoma of the head and neck: A case cohort and review of the literature

Matevz Skerget et al. Hematol Rep. .

Abstract

Extramedullary plasmacytoma of the head and neck is a rare indolent neoplasm. Radiotherapy is often the preferred treatment option with excellent local control and survival. The risk of local recurrence or transformation to multiple myeloma is 10-30%. In our case-cohort, thorough, sensitive initial evaluation for disseminated clonal disease and the incorporation of surgery led to excellent results with no recurrences or systemic progression.

Keywords: Extramedullary plasmacytoma; head and neck; radiotherapy; surgery.

PubMed Disclaimer

Conflict of interest statement

Conflict of interests: The authors declare no conflict of interests.

Figures

Figure 1.
Figure 1.
MRI STIR sequence of patient number 8 showing nasal extramedullary plasmacytoma.
See this image and copyright information in PMC

References

    1. Bachar G, Goldstein D, Brown D, et al. Solitary extramedullary plasmacytoma of the head and neck-Long-term outcome analysis of 68 cases. Head Neck 2008;30:1012-9. - PubMed
    1. Wen G, Wang W, Zhang Y, et al. Management of extramedullary plasmacytoma: Role of radiotherapy and prognostic factor analysis in 55 patients. Chin J Cancer Res 2017;29:438-46. - PMC - PubMed
    1. Alexiou C, Kau RJ, Dietzfelbinger H, et al. Extramedullary plasmacytoma. Cancer 1999;85:2305-14. - PubMed
    1. Goyal G, Bartley AC, Funni S, et al. Treatment approaches and outcomes in plasmacytomas: analysis using a national dataset. Leukemia 2018;32:1414-20. - PMC - PubMed
    1. Thumallapally N, Meshref A, Mousa M, Terjanian T. Solitary plasmacytoma: population-based analysis of survival trends and effect of various treatment modalities in the USA. BMC Cancer 2017;17:13. - PMC - PubMed

LinkOut - more resources