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. 2021 May;174(5):723-725.
doi: 10.7326/M20-5926. Epub 2020 Dec 8.

COVID-19 Symptoms: Longitudinal Evolution and Persistence in Outpatient Settings

Mayssam Nehme  1 , Olivia Braillard  1 , Gabriel Alcoba  2 , Sigiriya Aebischer Perone  3 , Delphine Courvoisier  1 , François Chappuis  4 , Idris Guessous  4 ; COVICARE TEAM
Collaborators, Affiliations

COVID-19 Symptoms: Longitudinal Evolution and Persistence in Outpatient Settings

Mayssam Nehme et al. Ann Intern Med. 2021 May.
No abstract available

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Conflict of interest statement

Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M20-5926.

Figures

Figure 1.
Figure 1.. Study flow diagram.
Out of the initial cohort of 703 participants, 669 ambulatory patients were ultimately included, excluding those who declined to participate (n = 31) or who lived outside the Geneva canton (n = 3). Reasons to suspend follow-up during the first 10 d were clinical recovery (≥10 d from symptom onset and 48 h without symptoms), patient wish, or hospitalization during follow-up. Attempts were made to assess all 669 participants at day 30–45 from diagnosis.
Figure 2.
Figure 2.. Longitudinal evolution of COVID-19 symptoms in outpatient settings (n = 669).
Forty of the participants were hospitalized during follow-up. Their data were included in the reported symptoms when available (up to hospitalization and again at day 30-45). COVID-19 = coronavirus disease 2019.
See this image and copyright information in PMC

Comment in

References

    1. Carfì A , Bernabei R , Landi F ; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA. 2020;324:603-605. [PMID: ] doi:10.1001/jama.2020.12603 - DOI - PMC - PubMed
    1. Tenforde MW , Kim SS , Lindsell CJ , et al; IVY Network Investigators. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems network — United States, March–June 2020. MMWR Morb Mortal Wkly Rep. 2020;69:993-998. [PMID: ] doi:10.15585/mmwr.mm6930e1 - DOI - PMC - PubMed
    1. Mahase E . Covid-19: What do we know about “long covid”. BMJ. 2020;370:m2815. [PMID: ] doi:10.1136/bmj.m2815 - DOI - PubMed
    1. Crosby SS . My COVID-19. Ann Intern Med. 2020. doi:10.7326/M20-5126 - DOI - PubMed
    1. Wu Z , McGoogan JM . Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020;323:1239-1242. [PMID: ] doi:10.1001/jama.2020.2648 - DOI - PubMed