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. 2021 Jan:256:400-404.
doi: 10.1016/j.ejogrb.2020.11.069. Epub 2020 Dec 1.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) universal screening in gravids during labor and delivery

Ricardo Savirón-Cornudella  1 , Ana Villalba  2 , Javier Zapardiel  3 , Mercedes Andeyro-Garcia  2 , Luis M Esteban  4 , Faustino R Pérez-López  5
Affiliations

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) universal screening in gravids during labor and delivery

Ricardo Savirón-Cornudella et al. Eur J Obstet Gynecol Reprod Biol. 2021 Jan.

Abstract

Objective: To screen pregnant women at risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during delivery using reverse-transcription polymerase chain reaction (RT-PCR) test and serum immunoglobulin (Ig) testing.

Method: Between March 31 st and August 31 st of 2020, consecutive pregnant women admitted for labor and delivery in a single hospital were screened for SARS-CoV-2 with nasopharyngeal RT-PCR swab tests and detection of serum IgG and IgM.

Results: We studied 266 pregnant women admitted for labor and delivery. The prevalence of acute or past SARS-CoV-2 infection was 9.0 %, including (i) two cases with respiratory symptoms of SARS-Co-V-2 infection and positive RT-PCR; (ii) four asymptomatic women with positive RT-PCR without clinical symptoms and negative serological tests between two and 15 weeks later; and (iii) two women with false positive RT-PCR due to technical problems. All newborns of the 6 pregnant women with RT-PCR positive had negative RT-PCR and did not require Neonatal Intensive Care Unit admission. There were eighteen asymptomatic women with positive serological IgG tests and negative RT-PCR.

Conclusion: In our cohort of gravids, we found 2.2 % of women with positive RT-PRC tests and 6.7 % with positive serological tests during the first wave of the SARS-CoV-2 pandemic.

Keywords: COVID-19; Delivery; Reverse-transcription polymerase chain reaction (RT-PCR); SARS-CoV-2; Screening; serum immunoglobulins.

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Conflict of interest statement

Declaration of Competing Interest The authors report no conflicts of interest and are alone responsible for the content and the writing of the article.

Figures

Fig. 1
Fig. 1
Flowchart of the SARS-CoV-2 screening and results in 266 pregnant women during delivery.
See this image and copyright information in PMC

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