Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2021 Apr;21(4):e402-e409.
doi: 10.1016/j.clml.2020.11.011. Epub 2020 Nov 20.

The Burden in Caregivers of Multiple Myeloma Patients Undergoing Outpatient Autologous Stem-Cell Transplantation Compared to Inpatient Transplantation

Massimo Martino  1 , Annalisa Pitino  2 , Giovanni Tripepi  3 , Annalisa Paviglianiti  4 , Letteria Russo  4 , Giuseppa Cusumano  4 , Antonio Rossetti  4 , Pasquale Fabio Provenzano  4 , Gaetana Porto  4 , Nicola Meliambro  4 , Salvatore Gallo  4 , Domenico Porcino  4 , Valentina Romeo  4 , Tiziana Gangemi  4 , Graziella D'Arrigo  3 , Lucrezia Imbalzano  4 , Giuseppe Console  4 , Mercedes Gori  2
Affiliations
Observational Study

The Burden in Caregivers of Multiple Myeloma Patients Undergoing Outpatient Autologous Stem-Cell Transplantation Compared to Inpatient Transplantation

Massimo Martino et al. Clin Lymphoma Myeloma Leuk. 2021 Apr.

Abstract

Background: The application of different models of autologous stem-cell transplantation (ASCT) in multiple myeloma has demonstrated the feasibility and safety of outpatient-based programs of care. Although several systematic reviews have evaluated the burden of caregivers, only a few studies have included outpatient ASCT.

Patients and methods: The feelings of lack of family support, daily activities, and general health were compared between caregivers of 2 groups of patients with multiple myeloma who underwent inpatient (n = 71) or outpatient (n = 25) ASCT.

Results: The 3 features did not significantly differ between the 2 study groups at baseline, before, and 3 months after ASCT. Multivariate modeling showed that the baseline values were significantly related to the changes in study outcomes independent of patient and caregiver characteristics. Other correlates were caregivers' work and patient age for impact on daily activities and disease burden across time for impact on general health (all P < .05).

Conclusion: The outpatient model neither improves nor impairs global caregivers' burden compared to standard ASCT care. Further research is needed to confirm this observation and to better assess the burden and quality of life of caregivers and their influence on patient outcomes and quality of life.

Keywords: ASCT; Caregivers; Inpatients; Multiple myeloma; Outpatients.

PubMed Disclaimer

Publication types