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. 2020 Nov 16;6(1):56.
doi: 10.1186/s40942-020-00259-4.

25 vs. 27-gauge micro-incision vitrectomy surgery for visually significant macular membranes and full-thickness macular holes: a retrospective study

Gordon T Brown  1 , Sangeethabalasri Pugazhendhi  2 , Robert M Beardsley  2 , John W Karth  2 , Peter A Karth  2 , Allan A Hunter  2
Affiliations

25 vs. 27-gauge micro-incision vitrectomy surgery for visually significant macular membranes and full-thickness macular holes: a retrospective study

Gordon T Brown et al. Int J Retina Vitreous. .

Abstract

Background: To evaluate visual and safety outcomes for 25-gauge (25G) and 27-gauge (27G) micro-incision vitrectomy platforms (MIVS) for the treatment of epiretinal membrane and full-thickness macular holes.

Methods: Retrospective analysis of all patients who underwent internal limiting membrane (ILM) peel surgery from January 2017 through December 2018. 207 cases met the eligibility criteria for inclusion. Primary endpoint was post-operative Best-Corrected Distance Visual Acuity (BCVA) at 6 months.

Results: For all patients combined, mean logMAR BCVA improved from 0.57 (± 0.40) to 0.37 (± 0.36) post-operatively (p < 0.001). For 25G ERMs, logMAR BCVA improved from 0.51 (± 0.28) to 0.30 (± 0.25) post-operatively (p < 0.001). For 27G ERMs, logMAR BCVA improved from 0.33 (± 0.28) to 0.28 (± 0.27) post- operatively (p = 0.15). For 25G FTMHs, logMAR BCVA improved from 0.87 (± 0.48) to 0.51 (± 0.44) post-operatively (p < 0.001). For 27G FTMHs, logMAR BCVA changed from 0.89 (± 0.47) to 0.96 (± 0.60).

Conclusion: Final visual outcomes improved for both 25G and 27G ERM groups and the 25G FTMH group. Both 25G and 27G were safe and well tolerated MIVS platforms for the treatment of ERM and FTMH.

Keywords: 25-gauge; 27-gauge; Epiretinal membrane; MIVS; Macular hole; Macular peel; Micro-incision vitrectomy surgery.

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Conflict of interest statement

The authors have no conflicts of interest or financial disclosures to declare.

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References

    1. Schönfeld CL. 23- vs 20-gauge pars plana vitrectomy in combination with bimanual microincisional cataract surgery (b-MICS) for the treatment of macular hole and cataract as a one-step procedure. Eye (Lond) 2013;27:952–958. doi: 10.1038/eye.2013.118. - DOI - PMC - PubMed
    1. Wimpissinger B, Kellner L, Brannath W, et al. 23-gauge versus 20-gauge system for pars plana vitrectomy: a prospective randomised clinical trial. Br J Ophthalmol. 2008;92:1483–1487. doi: 10.1136/bjo.2008.140509. - DOI - PubMed
    1. Kim M, Park YS, Lee DH, et al. Comparison of surgical outcome of 23-gauge and 25-gauge microincision vitrectomy surgery for management of idiopathic epiretinal membrane in pseudophakic eyes. Retina. 2015;35:2115–2120. doi: 10.1097/IAE.0000000000000598. - DOI - PubMed
    1. Lubiński W, Gosławski W, Podborączyńska-Jodko K, et al. Comparison of 27-gauge versus 25-gauge vitrectomy results in patients with epiretinal membrane: 6-month follow-up. Int Ophthalmol. 2020 doi: 10.1007/s10792-019-01250-1. - DOI - PubMed
    1. Naruse Z, Shimada H, Mori R. Surgical outcomes of 27-gauge and 25-gauge vitrectomy day surgery for proliferative diabetic retinopathy. Int Ophthalmol. 2019;39:1973–1980. doi: 10.1007/s10792-018-1030-z. - DOI - PubMed

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