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Case Reports
. 2021 Feb;27(2):648-650.
doi: 10.3201/eid2702.204632. Epub 2020 Dec 8.

Evidence of SARS-CoV-2 RNA in an Oropharyngeal Swab Specimen, Milan, Italy, Early December 2019

Case Reports

Evidence of SARS-CoV-2 RNA in an Oropharyngeal Swab Specimen, Milan, Italy, Early December 2019

Antonella Amendola et al. Emerg Infect Dis. 2021 Feb.

Abstract

We identified severe acute respiratory syndrome coronavirus 2 RNA in an oropharyngeal swab specimen collected from a child with suspected measles in early December 2019, ≈3 months before the first identified coronavirus disease case in Italy. This finding expands our knowledge on timing and mapping of novel coronavirus transmission pathways.

Keywords: COVID-19; Italy; Milan; SARS-CoV-2; SARS-CoV-2 RNA; coronavirus disease; oropharyngeal swab; respiratory infections; severe acute respiratory syndrome coronavirus 2; skin manifestations; viruses; zoonoses.

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References

    1. Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020;395:1771–8. 10.1016/S0140-6736(20)31103-X - DOI - PMC - PubMed
    1. Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. J Eur Acad Dermatol Venereol. 2020;34:e212–3. 10.1111/jdv.16387 - DOI - PubMed
    1. Percivalle E, Cambiè G, Cassaniti I, Nepita EV, Maserati R, Ferrari A, et al. Prevalence of SARS-CoV-2 specific neutralising antibodies in blood donors from the Lodi Red Zone in Lombardy, Italy, as at 06 April 2020. Euro Surveill. 2020;25:2001031. 10.2807/1560-7917.ES.2020.25.24.2001031 - DOI - PMC - PubMed
    1. Zehender G, Lai A, Bergna A, Meroni L, Riva A, Balotta C, et al. Genomic characterization and phylogenetic analysis of SARS-COV-2 in Italy. J Med Virol. 2020;92:1637–40. 10.1002/jmv.25794 - DOI - PMC - PubMed
    1. Giovanetti M, Angeletti S, Benvenuto D, Ciccozzi M. A doubt of multiple introduction of SARS-CoV-2 in Italy: A preliminary overview. J Med Virol. 2020;92:1634–6. 10.1002/jmv.25773 - DOI - PMC - PubMed

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