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Case Reports
. 2020 Nov 19:29:e00272.
doi: 10.1016/j.crwh.2020.e00272. eCollection 2021 Jan.

Coombs-negative haemolytic anaemia in pregnancy: A case report

Holly George  1 , E Haslett  1 , Mac Macheta  1
Affiliations
Case Reports

Coombs-negative haemolytic anaemia in pregnancy: A case report

Holly George et al. Case Rep Womens Health. .

Abstract

We present a rare case of Coombs-negative autoimmune haemolytic anaemia in a multiparous woman in secondary care. There were no known underlying medical or obstetric risk factors for haemolytic anaemia. Following extensive investigation and a therapeutic trial of oral corticosteroids, a diagnosis was made. Autoimmune haemolytic anaemia is potentially fatal, and prompt diagnosis with haematology input is essential to ensure maternal and fetal safety in pregnancy and the puerperium. With only a small number of cases of Coombs-negative autoimmune haemolytic anaemia reported in the literature, we present this rare case for discussion. We highlight the importance of thorough investigation of refractory anaemia in pregnancy and consider the associated challenges.

Keywords: Anaemia; Case report; Haematology; Maternal medicine; Obstetrics.

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Blood results.
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