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. 2020 Dec 7;54(1):e10253.
doi: 10.1590/1414-431X202010253. eCollection 2020.

Metabolic profile during pregnancy in BRISA birth cohorts of Ribeirão Preto and São Luís, Brazil

I C Rodrigues  1 , C Grandi  2 , V M F Simões  3 , R F L Batista  3 , L S Rodrigues  1 , V C Cardoso  1
Affiliations

Metabolic profile during pregnancy in BRISA birth cohorts of Ribeirão Preto and São Luís, Brazil

I C Rodrigues et al. Braz J Med Biol Res. .

Abstract

During pregnancy, metabolic changes that develop in women may increase the risk of diseases and conditions that may also harm the life of the growing fetus. The aim of the present study was to identify and compare the metabolic profile (MP) during pregnancy in two birth cohorts in 2010 in the cities of Ribeirão Preto (RP) and São Luís (SL), Brazil. Pregnant women (1393 in RP and 1413 in SL) were studied; information was obtained through questionnaires in addition to anthropometric, biochemical, and blood pressure measurements. Data are presented as means and proportions. To compare the characteristics of pregnant women in both cities, chi-squared and Student's t-tests were applied, with 5% significance level. Ribeirão Preto presented higher mean values than SL for pre-gestational body mass index (24.5 vs 23 kg/m2, P<0.001), systolic (108.4 vs 102.8 mmHg, P<0.001) and diastolic (65.9 vs 61.8 mmHg, P<0.001) blood pressure, total cholesterol (226.3 vs 213.7 mg/dL, P<0.001) and fractions, and glycemia (84.5 vs 80.2 mg/dL, P<0.001), except for triglycerides (P=0.135). Women from RP also showed higher rates of pre-gestational overweight and obesity compared with SL (40.1 vs 25.8%). In the present study, pregnant women in RP had a worse gestational metabolic profile than those in SL, with higher pre-gestational excess weight, indicating that nutritional transition was more advanced in the more developed city.

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Figure 1
Figure 1. Flowchart of the study population. RP: Ribeirão Preto; SL: São Luis.
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References

    1. Kac G, Velásquez-Meléndez G. The nutritional transition and the epidemiology of obesity in Latin America. Cad Saude Publica. 2003;19:S5–S4. doi: 10.1590/s0102-311x2003000700001. - DOI - PubMed
    1. Liu LX, Arany Z. Maternal cardiac metabolism in pregnancy. Cardiovasc Res. 2014;101:545–553. doi: 10.1093/cvr/cvu009. - DOI - PMC - PubMed
    1. Rich-Edwards JW, Fraser A, Lawlor DA, Catov JM. Pregnancy characteristics and women's future cardiovascular health: an underused opportunity to improve women's health? Epidemiol Rev. 2014;36:57–70. doi: 10.1093/epirev/mxt006. - DOI - PMC - PubMed
    1. Lawlor DA, Relton C, Sattar N, Nelson SM. Maternal adiposity-a determinant of perinatal and offspring outcomes? Nat Rev Endocrinol. 2012;8:679–688. doi: 10.1038/nrendo.2012.176. - DOI - PubMed
    1. Lawlor DA. The Society for Social Medicine John Pemberton lecture 2011. developmental overnutrition - an old hypothesis with new importance? Int J Epidemiol. 2013;42:7–2. doi: 10.1093/ije/dys209. - DOI - PubMed