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Review
. 2021 Jun 11;7(6):1369-1388.
doi: 10.1021/acsinfecdis.0c00646. Epub 2020 Dec 9.

Recent Insights into Emerging Coronavirus: SARS-CoV-2

Affiliations
Review

Recent Insights into Emerging Coronavirus: SARS-CoV-2

Zifang Shang et al. ACS Infect Dis. .

Abstract

The SARS-CoV-2 outbreak that emerged at the end of 2019 has affected more than 58 million people with more than 1.38 million deaths and has had an incalculable impact on the world . Extensive prevention and treatment measures have been implemented since the pandemic. In this Review, we summarize current understanding on the source, transmission characteristics, and pathogenic mechanism of SARS-CoV-2. We also detail the recent development of diagnostic methods and potential treatment strategies of COVID-19 with focus on the ongoing clinical trials of antibodies, vaccines, and inhibitors for combating the emerging coronavirus.

Keywords: COVID-19; SARS-CoV-2; antibody; diagnosis; inhibitor; pandemic; pathogenesis; therapy; transmission; vaccine.

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