Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Dec 9;13(1):560.
doi: 10.1186/s13104-020-05411-9.

Trends in the incidence and mortality of colorectal cancer in a brazilian city

Alex Rodrigues Moura  1   2 , Adriane Dórea Marques  3   4 , Mylena Santos Dantas  4 , Érika de Abreu Costa Brito  3   4 , Mariana do Rosário Souza  3 , Marcela Sampaio Lima  3   4 , Hianga Fayssa Fernandes Siqueira  3 , Angela Maria da Silva  3   4 , Ana Carolina Ribeiro Lisboa  3   4 , Marco Antonio Prado Nunes  3   4 , Marceli de Oliveira Santos  5 , Carlos Anselmo Lima  6   3   4
Affiliations

Trends in the incidence and mortality of colorectal cancer in a brazilian city

Alex Rodrigues Moura et al. BMC Res Notes. .

Abstract

Objectives: This study was conducted to analyze the trends in colorectal cancer (CRC) incidence and mortality in the city of Aracaju, Sergipe State, Brazil, between 1996 and 2015 with Joinpoint Regression Program 4.7.0.0 and to identify the geographical distribution of CRC in the municipality.

Results: A total of 1322 cases of CRC and 467 CRC-related deaths during the study period were included. In total, 40% of the incident cases and 43% of the deaths occurred in men, while 60% of the incident cases and 57% of the deaths occurred in women. Males who were 20 to 44 years old had the most significant trend in growth. Among women, those in the group aged 45 to 64 years had the highest observed annual percent change (APC). In both sexes, mortality was stable. Regarding the geographic distribution, there were constant hotspots in the northeast region of the municipality. This study showed a significant increase in incidence, mainly in young men between 20 and 44 years of age, but stable mortality in Aracaju.

Keywords: Colorectal cancer; Demography; Incidence; Mortality.

PubMed Disclaimer

Conflict of interest statement

The authors declare no other competing interests.

Figures

Fig. 1
Fig. 1
Incidence and mortality trends: a, b Incidence in females and males, respectively, considering the adjusted rates for the age groups 20–44 years, 45–64 years, + 65 years and all ages; c, d mortality in females and males, respectively, considering the adjusted rates for the age groups 45–64 years, + 65 years and all ages
Fig. 2
Fig. 2
Evolution of the density of incident cases of CRC on the kernel map
See this image and copyright information in PMC

References

    1. Da Silva De Carvalho Melo SP, Cesse EÂP, Lira PIC, Rissin A, De Sá Barreto Luna Callou Cruz R, Filho MB. Chronic noncommunicable diseases and associated factors among adults in an impoverished urban area of the brazilian northeast. Cienc e Saude Coletiva. 2019;24(8):3159–3168. doi: 10.1590/1413-81232018248.30742017. - DOI - PubMed
    1. Marley AR, Hongmei N. Epidemiology of colorectal cancer. Int J Mol Epidemiol Genet. 2016;7(3):105–114. - PMC - PubMed
    1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68(1):7–30. doi: 10.3322/caac.21442. - DOI - PubMed
    1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70(1):7–30. doi: 10.3322/caac.21590. - DOI - PubMed
    1. INCA. Estimativa/2020. Incidência de Câncer no Brasil. Rio de Janeiro: Ministério da Saúde; 2019. 120 p.