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Case Reports
. 2020 Oct;12(5):492-496.
doi: 10.5114/jcb.2020.100383. Epub 2020 Oct 30.

Salvage high-dose-rate interstitial brachytherapy for perineal recurrence of prostate cancer after surgery and radiotherapy: a case report

Andrea Vavassori  1 , Stefano Durante  1 , Matteo Augugliaro  1 , Stefania Comi  2 , Raffaella Cambria  2 , Federica Cattani  2 , Roberta Lazzari  1 , Deliu Victor Matei  3 , Ottavio De Cobelli  3   4 , Roberto Orecchia  5 , Barbara Alicja Jereczek-Fossa  1   4
Affiliations
Case Reports

Salvage high-dose-rate interstitial brachytherapy for perineal recurrence of prostate cancer after surgery and radiotherapy: a case report

Andrea Vavassori et al. J Contemp Brachytherapy. 2020 Oct.

Abstract

Perineal seeding of tumor cells from prostate cancer (PCa) is very rare, and no standard treatment exists for this atypical presentation with no evidence of distant metastases. Local excision or external beam radiotherapy are used as local salvage treatments for such perineal masses, including those occurring after biopsy, surgery, or interstitial brachytherapy. We report on a patient who presented no evidence of disease and no late urinary or gastrointestinal toxicities at 58 months after receiving high-dose-rate brachytherapy (HDR-BT) for perineal recurrence of PCa after radical prostatectomy and salvage external beam radiotherapy. To the best of our knowledge, this is the first case treated with HDR-BT in this scenario.

Keywords: interstitial HDR brachytherapy; perineal prostate cancer recurrence; reirradiation.

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Conflict of interest statement

The authors report no conflict of interest.

Figures

Fig. 1
Fig. 1
Pre-brachytherapy MRI (A) and choline PET (B)
Fig. 2
Fig. 2
Implant (A, B) and treatment plan (C)
Fig. 3
Fig. 3
Follow-up at 2 years with axial (A) and sagittal (B) MRI
See this image and copyright information in PMC

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