Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Oct 14;32(3):434-439.
doi: 10.37616/2212-5043.1143. eCollection 2020.

Transcatheter Aortic Valve Implantation: Bahrain Experience

Nooraldaem Yousif  1 , Suddharsan Subbramaniyam  1 , Babu Thevan  1 , Mohammad Amin  1 , Leena Sulaibikh  1 , Nazar Bukamal  2 , Habib Tareif  3 , Sadananda Shivappa  1 , Haitham Amin  1 , Husam A Noor  1
Affiliations

Transcatheter Aortic Valve Implantation: Bahrain Experience

Nooraldaem Yousif et al. J Saudi Heart Assoc. .

Abstract

Background: Transcatheter aortic valve implantation (TAVI) is a minimally invasive procedure that is considered a good alternative to surgical aortic valve replacement (sAVR) in selected patients. Our aim is to determine the baseline, procedural characteristics and one-year clinical outcomes of our TAVI registry.

Methods: This study is a retrospective observational analysis of a prospectively designed cohort comprising 81 consecutive patients treated at Mohammed bin Khalifa Cardiac Centre (MKCC) who were enrolled in Bahrain TAVI registry from February 2014 to February 2019. The clinical endpoints were defined according to the updated Valve Academic Research Consortium-2 (VARC-2) consensus document.

Results: Out of the 81 patients included in our study, there were 37 (45.7%) males. The mean age was 76.4 ± 8.9 years with a mean Logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE II) of 4.1 ± 2.5 and a mean Society of Thoracic Surgery (STS) Risk Score of 4.2 ± 3.5. Evolute-R valve was used for 36 (44.4%) patients, Edward Sapien for 26 patients (32.1%), and Core valve for 19 patients (23.5%). At one year follow up, all-cause death was reported in three (3.7%) patients; none of them was cardiovascular mortality. As per VARC-II criteria, no cases fulfilled the criteria of valve dysfunction but TAVI-related complications (i.e., TAV-in-TAV deployment) were reported in four (4.9%) cases. One (1.2%) case of major bleeding was encountered but no patient experienced life-threatening bleeding. Major vascular complications were documented in two patients (2.5%) only. Significant Acute Kidney Injury (AKI) occurred in two (2.5%) patients, both classified as stage-2 but no one deteriorated to stage-3 or hemodialysis. Seven (8.6%) patients required permanent pacemakers, and all were implanted during the index admission for TAVI. One patient (1.2%) had stroke and all survivors completed one-year follow up.

Conclusion: The TAVI program in Bahrain is encouraging and corresponds to the finest international centers outcomes in terms of procedural success and complications rate.

Keywords: Aortic stenosis; Aortic valve replacement; Corevalve; Edward Sapien; Evolute-R; Transcatheter aortic valve implantation.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Age and gender distribution among TAVI patients in Bahrain.
Fig. 2
Fig. 2
Types of valves in Bahrain TAVI registry.
See this image and copyright information in PMC

References

    1. Salam AA, Al-Khraif RM. Child mortality transition in the arabian Gulf: wealth, health system reforms, and development goals. Front Public Health. 2020;7:402. Published 2020 Jan 17. - PMC - PubMed
    1. Mokdad AH, Jaber S, Aziz MIA, AlBuhairan F, AlGhaithi A, AlHamad NM, et al. The state of health in the Arab world, 1990–2010: an analysis of the burden of diseases, injuries, and risk factors. Lancet. 2014;383:309–20. - PubMed
    1. Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, et al. PARTNER Trial Investigators. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med. 2010 Oct 21;363(17):1597–607. - PubMed
    1. Eleid MF, Holmes Jr DR. Transcatheter aortic valve replacement: state of the art and future directions. Annu Rev Med. 2017;68:15–28. - PubMed
    1. Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med. 2011;364:2187–98. - PubMed

LinkOut - more resources