Differences in bone conduction ocular vestibular evoked myogenic potentials to 500 Hz narrow band chirp stimulus and 500 Hz tone burst

Abstract

Objective: This study aims to investigate the differences of N1 latency, P1 latency and N1P1 amplitude in response to bone conducted 500 Hz tone burst and narrowband CE chirp stimulus in ocular vestibular evoked myogenic potentials (oVEMPs).

Methods: Forty-two healthy volunteers were included in this prospective study. Subjects with abnormal otological examinations and otological diseases were excluded. oVEMPs were randomly recorded in response to BC 500 Hz narrowband (NB) chirp stimulus and BC 500 Hz tone burst. The stimulus intensity was 50 dB nHL for both 500 Hz tone burst and 500 Hz NB CE chirp stimulus. P1 latency, N1 latency, and N1P1 amplitude were measured, and these measurements were compared between these two types of stimuli.

Results: Both types of stimuli elicited oVEMP in all subjects. N1 latency and P1 latency were significantly shorter (6.41 ms vs 10.84 ms; 10.64 ms vs 15.56 ms, respectively) for chirp stimulus (p < 0.05). N1P1 amplitude was significantly higher (11.64 vs 7.18 μV) for NB chirp stimulus (p < 0.05).

Conclusion: It is reasonable to conclude that the NB CE chirp stimulus is effective to elicit robust BC oVEMP in healthy subjects.

Keywords: Bone conduction; Chirp; Ocular vestibular evoked myogenic potentials; Tone burst.