Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2021 Apr 15;57(4):2003961.
doi: 10.1183/13993003.03961-2020. Print 2021 Apr.

Head-to-head comparison of SARS-CoV-2 antigen-detecting rapid test with self-collected nasal swab versus professional-collected nasopharyngeal swab

Andreas K Lindner  1   2 , Olga Nikolai  1   2 , Franka Kausch  1 , Mia Wintel  1 , Franziska Hommes  1 , Maximilian Gertler  1 , Lisa J Krüger  3 , Mary Gaeddert  3 , Frank Tobian  3 , Federica Lainati  3 , Lisa Köppel  3 , Joachim Seybold  4 , Victor M Corman  5   6 , Christian Drosten  5   6 , Jörg Hofmann  7 , Jilian A Sacks  8 , Frank P Mockenhaupt  1   2 , Claudia M Denkinger  9   2
Affiliations
Comparative Study

Head-to-head comparison of SARS-CoV-2 antigen-detecting rapid test with self-collected nasal swab versus professional-collected nasopharyngeal swab

Andreas K Lindner et al. Eur Respir J. .

Abstract

Supervised nasal self-sampling is a reliable alternative to professional nasopharyngeal sampling using a WHO-listed SARS-CoV-2 antigen-detecting rapid test. Self-sampling and potentially patient self-testing may be a future use case. https://bit.ly/3mup0hS

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: A.K. Lindner has nothing to disclose. Conflict of interest: O. Nikolai has nothing to disclose. Conflict of interest: F. Kausch has nothing to disclose. Conflict of interest: M. Wintel has nothing to disclose. Conflict of interest: F. Hommes has nothing to disclose. Conflict of interest: M. Gertler has nothing to disclose. Conflict of interest: L.J. Krüger has nothing to disclose. Conflict of interest: M. Gaeddert has nothing to disclose. Conflict of interest: F. Tobian has nothing to disclose. Conflict of interest: F. Lainati has nothing to disclose. Conflict of interest: L. Köppel has nothing to disclose. Conflict of interest: J. Seybold has nothing to disclose. Conflict of interest: V.M. Corman has nothing to disclose. Conflict of interest: C. Drosten has nothing to disclose. Conflict of interest: J. Hofmann has nothing to disclose. Conflict of interest: J.A. Sacks reports grants from UK Department of International Development (DFID, recently replaced by FCMO), World Health Organization (WHO) and Unitaid, during the conduct of the study. Conflict of interest: F.P. Mockenhaupt has nothing to disclose. Conflict of interest: C.M. Denkinger reports grants from Foundation of Innovative Diagnostics and Ministry of Science, Research and Culture, State of Baden Wuerttemberg, Germany, during the conduct of the study.

Comment in

References

    1. Foundation of Innovative New Diagnostics (FIND) . SARS-COV-2 Diagnostics Pipeline, 2020. www.finddx.org/covid-19/pipeline/ Date last accessed: 15 Oct 2020.
    1. World Health Organization . WHO Interim Guidance 11 September 2020. Antigen-detection in the Diagnosis of SARS-CoV-2 Infection using Rapid Immunoassays. https://apps.who.int/iris/bitstream/handle/10665/334253/WHO-2019-nCoV-An... Date last accessed: 15 Oct 2020.
    1. World Health Organization . WHO News Release 28 September 2020. Global Partnership to Make Available 120 Million Affordable, Quality COVID-19 Rapid Tests for Low- and Middle-income Countries. www.who.int/news-room/detail/28-09-2020-global-partnership-to-make-avail.... Date last accessed: 15 Oct 2020.
    1. Krueger LJ, Gaeddert M, Koeppel L, et al. . Evaluation of the accuracy, ease of use and limit of detection of novel, rapid, antigen-detecting point-of-care diagnostics for SARS-CoV-2. medRxiv 2020; preprint [10.1101/2020.10.01.20203836]. - DOI
    1. Tu YP, Jennings R, Hart B, et al. . Swabs collected by patients or health care workers for SARS-CoV-2 testing. N Engl J Med 2020; 383: 494–496. doi:10.1056/NEJMc2016321 - DOI - PMC - PubMed