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Case Reports
. 2020 Oct 9;6(12):1356-1359.
doi: 10.1016/j.jdcr.2020.09.023. eCollection 2020 Dec.

Dupilumab in HIV-positive patients: A case series report of 4 patients

Ameen Alawadhi  1 , Damira Karibayeva  2 , Alice B Gottlieb  1
Affiliations
Case Reports

Dupilumab in HIV-positive patients: A case series report of 4 patients

Ameen Alawadhi et al. JAAD Case Rep. .
No abstract available

Keywords: AD, atopic dermatitis; BSA, body surface area; HAART, highly active antiretroviral therapy; HIV; IGA, investigator global assessment; TH2, helper T cell type 2; atopic dermatitis; biologics; dupilumab.

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Figures

Fig 1
Fig 1
Erythematous lichenified scaly plaques and hyperpigmented papules with excoriations.
Fig 2
Fig 2
After 1 month of treatment with dupilumab.
Fig 3
Fig 3
Excoriated erythematous plaques over the trunk and extremities.
Fig 4
Fig 4
After 2 months of treatment with dupilumab.
See this image and copyright information in PMC

References

    1. Eichenfield L.F., Tom W.L., Chamlin S.L. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol. 2014;70(2):338–351. - PMC - PubMed
    1. Garg T., Sanke S. Inflammatory dermatoses in human immunodeficiency virus. Indian J Sex Transm Dis AIDS. 2017;38(2):113–120. - PMC - PubMed
    1. Mollanazar N., Qiu C., Aldrich J. Use of dupilumab in patients who are HIV-positive: report of four cases. Br J Dermatol. 2019;181(6):1311–1312. - PubMed
    1. Yechiel B. The changes in the T helper 1 (Th1) and T helper 2 (Th2) cytokine balance during HIV-1 infection are indicative of an allergic response to viral proteins that may be reversed by Th2 cytokine inhibitors and immune response modifiers - A review and hypothesis. Virus Genes. 2004;28(1):5–18. - PubMed
    1. Rudikoff D. The relationship between HIV infection and atopic dermatitis. Curr Allergy Asthma Rep. 2002;2(4):275–281. - PubMed

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