Revisiting anti-CTLA-4 antibodies in combination with PD-1 blockade for cancer immunotherapy
- PMID: 33307201
- DOI: 10.1016/j.annonc.2020.11.018
Revisiting anti-CTLA-4 antibodies in combination with PD-1 blockade for cancer immunotherapy
Conflict of interest statement
Disclosure IM: Advisor: Bristol-Myers Squibb (BMS), Roche, F-STAR, Boehringer Ingelheim, Biontech, Merck, Serono, Numab, Servier, Alligator, Pieris, AstraZeneca. Grants: Roche, BMS, Biontech, Alligator. Speaker honoraria. AstraZeneca, Merck Sharp & Dohme, BMS. MS: Consulting: Idera, Regeneron, Apexigen, Alligator, Verastem, Agenus, Rubius, Bristol-Myers, Genentech-Roche, Boston Pharmaceuticals, Servier, Adaptimmune, Immunocore, Dragonfly, Pierre-Fabre, Molecular Partners, Boehringer Ingelheim, Innate Pharma, Nektar, Pieris, Numab, Abbvie, Zelluna, Seattle Genetics, Genocea, GI Innovation, Chugai-Roche, Biontech, Lilly, Modulate Therapeutics, Array, AstraZeneca, Genmab. Stock Options: Evolveimmune, Nextcure, Torque-Repertoire, Adaptive Biotechnologies, Actym, Amphivena. Stock Ownership: Glaxo-Smith Kline, Johnson and Johnson.
Comment on
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Safety and efficacy of quavonlimab, a novel anti-CTLA-4 antibody (MK-1308), in combination with pembrolizumab in first-line advanced non-small-cell lung cancer.Ann Oncol. 2021 Mar;32(3):395-403. doi: 10.1016/j.annonc.2020.11.020. Epub 2020 Dec 2. Ann Oncol. 2021. PMID: 33276076 Clinical Trial.
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