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Review
. 2020 Dec;10(2):021101.
doi: 10.7189/jogh.10.021101.

The role of children in the transmission of SARS-CoV2: updated rapid review

Xue Li  1   2 , Wei Xu  2 , Marshall Dozier  3 , Yazhou He  2 , Amir Kirolos  2   4 , Zhongyu Lang  2 , Peige Song  1 , Evropi Theodoratou  2   5 ; UNCOVER
Affiliations
Review

The role of children in the transmission of SARS-CoV2: updated rapid review

Xue Li et al. J Glob Health. 2020 Dec.

Abstract

Background: Understanding carriage and transmission potential of SARS-CoV-2 in children is of paramount importance to understand the spread of virus in school and community settings.

Methods: We performed an updated rapid review to investigate the role of children in the transmission of SARS-CoV-2. We synthesized evidence for five categories and results are reported narratively.

Results: A total of 33 new studies were included for this review. We did not identify additional studies that reported documented cases of SARS-CoV-2 transmission by children. We identified 15 new studies that demonstrate children's susceptibility and transmission risk of SARS-CoV-2 with evidence provided on the chance of being index or secondary cases, the potential of faecal-oral transmission, and the possibility of asymptomatic transmission. There is little data on the transmission of SARS-CoV-2 in schools. There were three studies reporting COVID-19 school outbreaks in France (Oise), Australia (New South Wales) and Israel. The remaining four studies found that all reported cases did not infect any other pupils or staff. With data from seven studies and governmental websites, the proportion of children among all confirmed COVID-19 patients was estimated for 29 countries, varying from 0.3% (lowest in Spain) up to 13.8% (highest in Argentina). Lastly, we identified seven studies reporting on PIMS-TS linked to COVID-19 among paediatric patients.

Conclusions: There is somewhat limited evidence available for quantifying the extent to which children may contribute to overall transmission, but the balance of evidence so far suggests that children and schools play only a limited role in overall transmission.

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Conflict of interest statement

Competing interests: The authors completed the ICMJE Unified Competing Interest form (available upon request from the corresponding author), and declare no conflicts of interest.

Figures

Figure 1
Figure 1
Flowchart summarizing study identification and selection.
Figure 2
Figure 2
The proportion of children among the confirmed COVID-19 patients (data available for 29 countries).
See this image and copyright information in PMC

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Supplementary concepts