Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Dec 1;79(12):353-357.

Special Feature: Diagnosis and Treatment of Neuroangiostrongyliasis in Hawai'i

Affiliations

Special Feature: Diagnosis and Treatment of Neuroangiostrongyliasis in Hawai'i

Kenton Kramer et al. Hawaii J Health Soc Welf. .

Abstract

Angiostrongylus cantonensis is a metastrongylid lungworm of rats with a global distribution and the cause of neuroangiostrongyliasis in humans. In Hawai'i, neuroangiostrongyliasis cases have occurred sporadically since 1960; however, in 2001, the number of cases on Maui and Hawai'i Island began to increase significantly. Since most human treatment trials have been conducted in Thailand, where the disease is usually mild, there is a need to develop treatment protocols for Hawai'i, where there is a broader disease spectrum. In 2018, preliminary guidelines for the diagnosis and treatment of neuroangiostrongyliasis were developed for Hawai'i's physicians. This article summarizes those guidelines and provides additional recommendations for individuals who recently ingested an infected intermediate host.

Keywords: Angiostrongylus cantonensis; eosinophilic meningitis.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Number of Neuroangiostrongyliasis Cases Reported in the Hawaiian Islands by County and Year.

References

    1. Alicata JE. Angiostrongyliasis cantonensis (Eosinophilic Meningitis): Historical Events in its Recognition as a New Parasitic Disease of Man. J Wash Acad Sci. 1988;78((1)):38–46.
    1. Wallace G, Rosen L. Studies on eosinophilic meningitis. V. Molluscan hosts of Angiostrongylus cantonensis on Pacific Islands. Am J Trop Med Hyg. 1969;18((2)):06–216. - PubMed
    1. Nomura S, Lin PH. First case report of human infection with Haemostrongylus ratti Yokogawa. Taiwan No Ikai. 1945;3:589–592.
    1. Tiernan JR, Prociv P. Eosinophilic meningoencephalitis with permanent sequelae. Med J Aust. 1987;147((6)):294–295. - PubMed
    1. Eamsobhana P. Eosinophilic meningitis caused by Angiostrongylus cantonensis--a neglected disease with escalating importance. Trop Biomed. 2014;31((4)):569–578. - PubMed