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. 2020 Dec;48(6):454-459.
doi: 10.5152/TJAR.2020.18999. Epub 2020 Feb 17.

The Effect of Intravesical Diluted Bupivacaine on Catheter-Related Bladder Discomfort in Young and Middle-Aged Male Patients During Postanaesthetic Recovery

Alireza Pournajafian  1 , Mohammad Reza Ghodraty  1 , Shora Shafighnia  1 , Faranak Rokhtabnak  1 , Ali Khatibi  1 , Sina Tavoosian  1 , Mansoureh Ghayoomi  1
Affiliations

The Effect of Intravesical Diluted Bupivacaine on Catheter-Related Bladder Discomfort in Young and Middle-Aged Male Patients During Postanaesthetic Recovery

Alireza Pournajafian et al. Turk J Anaesthesiol Reanim. 2020 Dec.

Abstract

Objective: Catheter-related bladder discomfort (CRBD) that manifests as agitation and bladder hyperactivity is a common problem in young male patients. Local anaesthetics are typically recommended for this problem. Hence, this study was conducted to determine the effect of intravesical diluted bupivacaine on CRBD in young male patients during postanaesthetic recovery.

Methods: This double-blinded randomised clinical trial included 68 consecutive patients, aged 20-60 years, who underwent urinary catheterisation during surgery and anaesthesia at a university hospital during 2017-2018. Patients were randomly assigned to receive either 50 ml of intravesical diluted (0.2%) bupivacaine (n=37) or normal saline (n=31). The incidence and severity of CRBD were then evaluated in PACU and compared between the two groups.

Results: In this study, 16.2% of patients in the bupivacaine group and 83.9% in the saline group had discomfort at arrival in the recovery room, exhibiting a significant intergroup difference (p=0.0001). Moreover, after 15-20 min, the incidence of CRBD was 16.2% and 90.3% in the bupivacaine and normal saline groups, respectively, which again demonstrated a significant statistical difference (p=0.0001). In addition, the severity of CRBD was lower in the bupivacaine group, during both periods (p=0.005). The saline group reported significantly higher use of pethidine and midazolam (p=0.005).

Conclusion: It may be concluded that intravesical diluted bupivacaine can significantly decrease the incidence and severity of CRBD in young male patients during recovery from anaesthesia. Therefore, the use of this method is highly recommended.

Keywords: Bupivacaine; male; urinary bladder; urinary catheters.

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Conflict of interest statement

Conflict of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Incidence and severity of CRBD immediately after clamp release in the groups CRBD: catheter-related bladder discomfort
Figure 2
Figure 2
Incidence and severity of CRBD 15–20 min after clamp release in the groups CRBD: catheter-related bladder discomfort
See this image and copyright information in PMC

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