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Comment
. 2021 Jan;132(1):108-109.
doi: 10.1213/ANE.0000000000005206.

Linear Regression in Medical Research

Patrick Schober  1 , Thomas R Vetter  2
Affiliations
Comment

Linear Regression in Medical Research

Patrick Schober et al. Anesth Analg. 2021 Jan.
No abstract available

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Figures

Figure.
Figure.
Table 2 given in Müller-Wirtz et al, showing the estimated relationships between tissue (or plasma) propofol concentrations and exhaled propofol concentrations. The authors appropriately report the 95% confidence intervals as a measure of the precision of their estimates, as well as the coefficient of determination (R2). The presented values indicate, for example, that (1) the exhaled propofol concentrations are estimated to increase on average by 4.6 units, equal to the slope (regression) coefficient, for each 1-unit increase of plasma propofol concentration; (2) the “true” mean increase could plausibly be expected to lie anywhere between 3.6 and 5.7 units as indicated by the slope coefficient’s confidence interval; and (3) the R2 suggests that about 71% of the variability in the exhaled concentration can be explained by its relationship with plasma propofol concentrations.
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References

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