Procalcitonin Is Useful for Antibiotic Deescalation in Sepsis
- PMID: 33315698
- DOI: 10.1097/CCM.0000000000004776
Procalcitonin Is Useful for Antibiotic Deescalation in Sepsis
Conflict of interest statement
Dr. Ferrer has received honoraria from Thermofisher and Biomereux. Dr. Plata-Menchaca has disclosed that she does not have any potential conflicts of interest.
Comment in
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Procalcitonin Is Useful for Antibiotic Deescalation in Sepsis and Septic Shock: Beware of Some Confounders!Crit Care Med. 2021 Jun 1;49(6):e659. doi: 10.1097/CCM.0000000000004934. Crit Care Med. 2021. PMID: 34011841 No abstract available.
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The authors reply.Crit Care Med. 2021 Jun 1;49(6):e660-e661. doi: 10.1097/CCM.0000000000004997. Crit Care Med. 2021. PMID: 34011842 No abstract available.
References
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- Ferrer R, Martin-Loeches I, Phillips G, et al. Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: Results from a guideline-based performance improvement program. Crit Care Med. 2014; 42:1749–1755
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- Cassini A, Högberg LD, Plachouras D, et al. Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European economic area in 2015: A population-level modelling analysis. Lancet Infect Dis. 2019; 19:56–66
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- Tabah A, Bassetti M, Kollef MH, et al. Antimicrobial de-escalation in critically ill patients: A position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP). Intensive Care Med. 2020; 46:245–265
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- Balk RA, Kadri SS, Cao Z, et al. Effect of procalcitonin testing on health-care utilization and costs in critically ill patients in the United States. Chest. 2017; 151:23–33
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- De Bus L, Depuydt P, Steen J, et al. Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: The DIANA study. Intensive Care Med. 2020; 46:1404–1417
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