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Case Reports
. 2021 Jul-Aug;37(4):e134-e136.
doi: 10.1097/IOP.0000000000001909.

Primary Adnexal Signet-Ring Cell/Histiocytoid Carcinoma

Stephen Stewart  1 , Joe Houghton  2 , Sri Kamalarajah  1 , David Curragh  1
Affiliations
Case Reports

Primary Adnexal Signet-Ring Cell/Histiocytoid Carcinoma

Stephen Stewart et al. Ophthalmic Plast Reconstr Surg. 2021 Jul-Aug.

Abstract

An 84-year-old man presented with a 2-year history of a progressive left-sided ptosis. Examination demonstrated a mechanical ptosis and concentric constriction of the palpebral aperture. CT imaging revealed demonstrated diffuse soft tissue infiltration of the upper and lower eyelids with extension into the anterior orbit. This case was diagnostically challenging because of a history of multiple other primary tumors. However, clinicoradiologic and histopathologic findings were consistent with a diagnosis of primary adnexal signet-ring cell/histiocytoid carcinoma. The patient underwent surgical excision but local recurrence was noted 2 months postoperatively.

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Conflict of interest statement

The authors have no financial or conflicts of interest to disclose.

References

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    1. Yates JR, Mines MJ, Subramanian PS, et al. Periocular histiocytoid carcinoma: potential diagnostic challenges. Ocul Oncol Pathol. 2019;5:94–101.
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    1. Bianciotto C, Demirci H, Shields CL, et al. Metastatic tumors to the eyelid: report of 20 cases and review of the literature. Arch Ophthalmol. 2009;127:999–1005.

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