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. 2020 Oct 1;46(10):349-353.
doi: 10.14745/ccdr.v46i10a07.

Acute flaccid myelitis in Canada, 2018 to 2019

Catherine Dickson  1 , Brigitte Ho Mi Fane  1 , Susan G Squires  1
Affiliations

Acute flaccid myelitis in Canada, 2018 to 2019

Catherine Dickson et al. Can Commun Dis Rep. .

Abstract

Starting in 2014, biennial clusters of acute flaccid myelitis (AFM), frequently described as "polio-like" illness, have been reported across the United States and elsewhere, often linked to enteroviruses. To assess AFM trends in Canada, we reviewed the Canadian Acute Flaccid Paralysis Surveillance System (CAFPSS) for cases reported during the 2018 and 2019 calendar years that meet the Centers for Disease Control and Prevention case definitions for AFM. A total of 10 cases (8 in 2018 and 2 in 2019) met the confirmed AFM case definition and 30 (26 in 2018 and 4 in 2019) met the probable AFM case definition. Sixty percent of confirmed and probable cases were younger than five years old, and all cases had symptom onset between the months of July and October. Enteroviruses were detected in 50% of confirmed cases. At the time of writing this report, 2020 AFM data were not yet available; it is unknown if a spike in AFM cases will be seen in 2020.

Keywords: acute flaccid myelitis; acute flaccid paralysis; enterovirus; infectious disease; surveillance.

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Conflict of interest statement

Competing interests: None.

Figures

Figure 1
Figure 1
Number of confirmed AFP cases in Canada, by year, 1996–2019 (n=1,070)a Abbreviation: AFP, acute flaccid paralysis a As of July 24, 2020
Figure 2
Figure 2
Confirmed AFP cases reported to PHAC by paralysis or weakness onset date and by AFM status, 2018–2019a Abbreviations: AFM, acute flaccid myelitis; AFP, acute flaccid paralysis; PHAC, Public Health Agency of Canada a As of July 24, 2020
See this image and copyright information in PMC

References

    1. Sejvar JJ, Lopez AS, Cortese MM, Leshem E, Pastula DM, Miller L, Glaser C, Kambhampati A, Shioda K, Aliabadi N, Fischer M, Gregoricus N, Lanciotti R, Nix WA, Sakthivel SK, Schmid DS, Seward JF, Tong S, Oberste MS, Pallansch M, Feikin D. Acute flaccid myelitis in the United States, August–December 2014: results of nationwide surveillance. Clin Infect Dis 2016. Sep;63(6):737–45. 10.1093/cid/ciw372 - DOI - PMC - PubMed
    1. Ayers T, Lopez A, Lee A, Kambhampati A, Nix WA, Henderson E, Rogers S, Weldon WC, Oberste MS, Sejvar J, Hopkins SE, Pallansch MA, Routh JA, Patel M. Acute flaccid myelitis in the United States: 2015-2017. Pediatrics 2019. Nov;144(5):e20191619. 10.1542/peds.2019-1619 - DOI - PubMed
    1. Lopez A, Lee A, Guo A, Konopka-Anstadt JL, Nisler A, Rogers SL, Emery B, Nix WA, Oberste S, Routh J, Patel M. Vital signs: surveillance for acute flaccid myelitis—United States, 2018. MMWR Morb Mortal Wkly Rep 2019. Jul;68(27):608–14. 10.15585/mmwr.mm6827e1 - DOI - PubMed
    1. Yea C, Bitnun A, Robinson J, Mineyko A, Barton M, Mah JK, Vajsar J, Richardson S, Licht C, Brophy J, Crone M, Desai S, Hukin J, Jones K, Muir K, Pernica JM, Pless R, Pohl D, Rafay MF, Selby K, Venkateswaran S, Bernard G, Yeh EA. Longitudinal outcomes in the 2014 acute flaccid paralysis cluster in Canada: a nationwide study. J Child Neurol 2017. Mar;32(3):301–7. 10.1177/0883073816680770 - DOI - PubMed
    1. Skowronski DM, Chambers C, Sabaiduc S, Murti M, Gustafson R, Pollock S, Hoyano D, Rempel S, Allison S, De Serres G, Dickinson JA, Tellier R, Fonseca K, Drews SJ, Martineau C, Reyes-Domingo F, Wong T, Tang P, Krajden M. Systematic community- and hospital-based surveillance for enterovirus-D68 in three Canadian provinces, August to December 2014. Euro Surveill 2015;20(43):pii=30047. 10.2807/1560-7917.ES.2015.20.43.30047 - DOI - PubMed