Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2021 Feb;126(2):e55-e57.
doi: 10.1016/j.bja.2020.11.004. Epub 2020 Dec 13.

A randomised pilot trial of combined cognitive and physical exercise prehabilitation to improve outcomes in surgical patients

Kimberly F Rengel  1 , Nitin Mehdiratta  2 , Susan W Vanston  3 , Kristin R Archer  4 , James C Jackson  5 , Jennifer L Thompson  6 , Pratik P Pandharipande  7 , Christopher G Hughes  7
Affiliations
Randomized Controlled Trial

A randomised pilot trial of combined cognitive and physical exercise prehabilitation to improve outcomes in surgical patients

Kimberly F Rengel et al. Br J Anaesth. 2021 Feb.
No abstract available

Keywords: acquired disability; major surgery; postoperative neurocognitive disorder; prehabilitation; quality of life.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Fig 1
Fig 1
Graphic representation of the change in raw scores on each assessment from baseline. A positive change on the graph from baseline on the Pattern Comparison, Dimensional Change Card Sort (DCCS), and Flanker tests indicate an improvement in cognitive function, whereas zero would be no change from baseline, and a negative change would be a decrease in cognition. Positive changes in grip strength and 2-MWT indicate improvement in physical function. Conversely, a positive change in Instrumental Activities of Daily Living (IADLs) correlates to more disability and worse functional status.
See this image and copyright information in PMC

References

    1. Evered L., Silbert B., Knopman D.S. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery – 2018. Br J Anaesth. 2018;121:1005–1012. - PMC - PubMed
    1. Lawrence V.A., Hazuda H.P., Cornell J.E. Functional independence after major abdominal surgery in the elderly. J Am Coll Surg. 2004;199:762–772. - PubMed
    1. Quinlan N., Rudolph J.L. Postoperative delirium and functional decline after noncardiac surgery. J Am Geriatr Soc. 2011;59(Suppl 2):S301–S304. - PubMed
    1. Lopez P., Pinto R.S., Radaelli R. Benefits of resistance training in physically frail elderly: a systematic review. Aging Clin Exp Res. 2018;30:889–899. - PubMed
    1. Gillis C., Li C., Lee L. Prehabilitation versus rehabilitation: a randomized control trial in patients undergoing colorectal resection for cancer. Anesthesiology. 2014;121:937–947. - PubMed

Publication types

LinkOut - more resources