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. 2021 Jul;16(7):1425-1426.
doi: 10.4103/1673-5374.301005.

Phase-specific manipulation of neuronal activity: a promising stroke therapy approach

Affiliations

Phase-specific manipulation of neuronal activity: a promising stroke therapy approach

Dennis A Turner et al. Neural Regen Res. 2021 Jul.
No abstract available

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
Conceptual framework for phase-specific manipulation of neuronal activity in stroke therapy. This figure depicts the relative time frame for stroke therapies. Initially suppressing neuronal activity may be beneficial. Then, there is a transition period as the brain prepares the environment for recovery. Finally, during the neurorestoration phase, modulation of neuronal activity is expected to facilitate structural and functional recovery of cerebral vasculature and neural network. Therapy targeting both early and later phases may be synergistic in improving outcome, as shown by the recovery trajectory line (purple).

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