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Case Reports
. 2020 Nov 6:7:30-32.
doi: 10.1016/j.jdcr.2020.10.029. eCollection 2021 Jan.

Diffuse xanthomas in a patient with primary biliary cholangitis and lipoprotein X

Jasmine Harris  1 , Severine Cao  2 , Grace Hile  2 , Milad Eshaq  2
Affiliations
Case Reports

Diffuse xanthomas in a patient with primary biliary cholangitis and lipoprotein X

Jasmine Harris et al. JAAD Case Rep. .
No abstract available

Keywords: PBC, primary biliary cholangitis; lipoprotein X; liver transplantation; primary biliary cirrhosis; xanthoma.

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Figures

Fig 1
Fig 1
Numerous xanthomas in a patient with lipoprotein X in the setting of PBC. A, Xanthelasma: soft, yellow-brown plaques along the medial canthi and the upper eyelids. B, Xanthoma striatum palmare: multiple soft, yellow-brown papules coalescing into plaques across the palmar hands, favoring the palmar creases. C, Intertriginous xanthomas: soft, yellow-brown papules coalescing into plaques within the axilla. D, Tuberous xanthomas: multiple soft, yellow-brown papules and nodules symmetrically distributed along the dorsal aspect of the digits of the hand. PBC, Primary biliary cholangitis.
See this image and copyright information in PMC

References

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    1. Suzuki L., Hirayama S., Fukui M. Lipoprotein-X in cholestatic patients causes xanthomas and promotes foam cell formation in human macrophages. J Clin Lipidol. 2017;11(1):110–118. - PubMed
    1. Brandt E.J., Regnier S.M., Leung E.K. Management of lipoprotein X and its complications in a patient with primary sclerosing cholangitis. Clin Lipidol. 2015;10(4):305–312. - PMC - PubMed
    1. Miida T., Hirayama S. Controversy over the atherogenicity of lipoprotein-X. Curr Opin Endocrinol Diabetes Obes. 2019;26(2):117–123. - PubMed

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