Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 Jun 15;72(12):e1090-e1092.
doi: 10.1093/cid/ciaa1856.

Proton Pump Inhibitors and Incident Clostridioides difficile Infection: Beyond Controversy, Pragmatic Approaches Are Needed

Affiliations
Editorial

Proton Pump Inhibitors and Incident Clostridioides difficile Infection: Beyond Controversy, Pragmatic Approaches Are Needed

Javier A Villafuerte-Gálvez. Clin Infect Dis. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Model for confounding despite the self-controlled case series design. Abbreviations: CDI, Clostridioides difficile infection; PPI, proton-pump inhibitor.

Comment on

References

    1. Cunningham R, Dale B, Undy B, Gaunt N. Proton pump inhibitors as a risk factor for Clostridium difficile diarrhoea. J Hosp Infect 2003; 54:243–5. - PubMed
    1. William JH, Danziger J. Proton-pump inhibitor-induced hypomagnesemia: current research and proposed mechanisms. World J Nephrol 2016; 5:152–7. - PMC - PubMed
    1. Almario CV, Chey WD, Spiegel BMR. Increased risk of COVID-19 among users of proton pump inhibitors. Am J Gastroenterol 2020; 115:1707–15. - PMC - PubMed
    1. Gomm W, von Holt K, Thomé F, et al. . Association of proton pump inhibitors with risk of dementia: a pharmacoepidemiological claims data analysis. JAMA Neurol 2016; 73:410–6. - PubMed
    1. Sehested TSG, Gerds TA, Fosbøl EL, et al. . Long-term use of proton pump inhibitors, dose-response relationship and associated risk of ischemic stroke and myocardial infarction. J Intern Med 2018; 283:268–81. - PubMed

MeSH terms

Substances