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Comment
. 2020 Dec 15;53(6):1123-1125.
doi: 10.1016/j.immuni.2020.11.013.

It's a Phase That EBF1 Is Going Through

Barbara L Kee  1
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It's a Phase That EBF1 Is Going Through

Barbara L Kee. Immunity. .
Free article

Abstract

EBF1 is a pioneer transcription factor involved in B lymphocyte specification. In this issue of Immunity, Wang et al. localize EBF1's pioneering activity to a prion-like domain that mediates recruitment of the nucleosome remodeler Brg1 and FUS-assisted liquid-liquid phase separation.

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Conflict of interest statement

Declarations of Interest Barbara L. Kee is on the external advisory board for Century Therapeutics.

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