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. 2020:25:100220.
doi: 10.1016/j.ctarc.2020.100220. Epub 2020 Oct 10.

Epidemiology of breast cancer in women based on diagnosis data from oncologists and senologists in Algeria

F Smaili  1 , A Boudjella  2 , A Dib  3 , S Braikia  3 , H Zidane  3 , R Reggad  3 , A Bendib  4 , A Abdelouahab  4 , F Bereksi-Reguig  5 , D Yekrou  5 , A Bentouati  5 , T Filali  6 , A Chirouf  6 , N Djehal  6 , H Mahfouf  7 , F Mechiat  7 , H Tadjerouni  7 , C Sedkaoui  8 , M Hikem  8 , A Amber  8 , K Bouzid  9 , A Ladjeroud  9 , S Ghomari  10 , H Aris  10 , S Saidi  10 , R Larhbali  10 , M A Saidi  10 , A Haddouche  11 , M Kedar  12 , A Bounedjar  1 , S Talha  1 , W Benbrahim  13 , A Ammari  13 , A Boushaba  14 , A Rabah  14 , N Ameziane  14 , F Benabdallah  14 , H Djedi  15 , N Kouadri  15 , A Bensalem  16 , S Djeghim  16 , M Oukkal  17 , F Hadjam  17 , B Larbaoui  18 , K Rekai  18 , N Azzouz  18 , A Badaoui  19 , M Abid  20 , M Abada  21 , A Moussei  22 , F Benmehidi  23 , N Benzidane  4 , K Boualga  24 , S Mesli  24
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Free article

Epidemiology of breast cancer in women based on diagnosis data from oncologists and senologists in Algeria

F Smaili et al. Cancer Treat Res Commun. 2020.
Free article

Abstract

Background: Breast cancer (BC) is a major health issue threatening women's life. No reliable epidemiological data on BC diagnosed by oncologists/senologists are available in Algeria.

Methods: The BreCaReAl study, a non-interventional prospective cohort study, included adult women with confirmed BC in Algeria. Disease incidence, patients and disease characteristics, treatment patterns, and mortality rate were recorded up to 12 months of follow-up.

Results: Overall, 1,437 patients were analysed: median age was 48 [41;57] years and 337 (23.5%) women had a family history of BC. BC incidence was 22.3 (95% CI: 21.5; 23.2) cases per 100,000 inhabitants over 8 months. Delayed diagnosis was reported in 400 (29.2%) patients. First line of treatments were mainly chemotherapy and surgery. Twenty-eight serious adverse events were reported including 10 (37.0%) events which led to death. Mortality rate reached 3.2% at 12 months CONCLUSION: A delayed diagnosis highlights the importance of implementing more effective screening strategies.

Keywords: Breast cancer; Diagnosis; Incidence; Mortality; Treatment.

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