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. 2021 Jan;28(1):5-14.
doi: 10.1038/s41418-020-00666-y. Epub 2020 Dec 17.

From the T-cell receptor to cancer therapy: an interview with Tak W. Mak

Tak W Mak  1   2   3   4
Affiliations

From the T-cell receptor to cancer therapy: an interview with Tak W. Mak

Tak W Mak. Cell Death Differ. 2021 Jan.

Abstract

This interview is part of a series of articles to mark the 25th anniversary of the launching of Cell Death and Differentiation.

PubMed Disclaimer

Conflict of interest statement

TWM is a co-founder of Agios Pharmaceuticals, Treadwell Therapeutics and Tcryption.

Figures

Fig. 1
Fig. 1
Tak Wah Mak
Fig. 2
Fig. 2
Dr Mak performing experiments at the Princess Margaret Cancer Centre in Toronto.
Fig. 3
Fig. 3
Mapping cancer pathways.
Fig. 4
Fig. 4
Aiming always high!
See this image and copyright information in PMC

References

    1. Till JE, McCulloch E. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res. 1961;14:213–22. doi: 10.2307/3570892. - DOI - PubMed
    1. Mak TW, Penrose D, Gamble C, Bernstein A. The Friend spleen focus-forming virus (SFFV) genome: fractionation and analysis of SFFV and helper virus-related sequences. Virology. 1978;87:73–80. doi: 10.1016/0042-6822(78)90159-9. - DOI - PubMed
    1. Chen IS, Mak TW, O’Rear JJ, Temin HM. Characterization of reticuloendotheliosis virus strain T DNA and isolation of a novel variant of reticuloendotheliosis virus strain T by molecular cloning. J Virol. 1981;40:800–11. doi: 10.1128/jvi.40.3.800-811.1981. - DOI - PMC - PubMed
    1. Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell. 1986;46:705–16. doi: 10.1016/0092-8674(86)90346-6. - DOI - PubMed
    1. Clark SP, Mak TW. Complete nucleotide sequence of an infectious clone of Friend spleen focus-forming provirus: gp55 is an envelope fusion glycoprotein. Proc Natl Acad Sci U S A. 1983;80:5037–41. doi: 10.1073/pnas.80.16.5037. - DOI - PMC - PubMed

Substances

Personal name as subject