Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Dec;32(4):192-198.
doi: 10.5371/hp.2020.32.4.192. Epub 2020 Dec 3.

Vitamin D Levels in Patients with Low-energy Hip Fractures

Jaehwi Han  1 , Youngho Cho  1 , Seungmin Jee  1 , Seongwoo Jo  1
Affiliations

Vitamin D Levels in Patients with Low-energy Hip Fractures

Jaehwi Han et al. Hip Pelvis. 2020 Dec.

Abstract

Purpose: To evaluate serum 25(OH) vitamin D levels in patients with low-energy hip fractures.

Materials and methods: Among 983 patients who underwent hip fracture surgery between August 2013 and March 2019, 732 patients were evaluated. The remaining patients were excluded due to the presence of one or more of the following: metastatic bone tumor, metabolic bone disease other than osteoporosis, fracture due to high-energy injury, atypical femoral fracture, and no blood test. We collected patient's data about age, sex male female, date of injury, a place of residence, fracture type, preinjury ambulation ability according to their Koval score, and their serum level of 25(OH) vitamin D. The mean age was 79.3 years (60-104 years). The sample was comprised of 530 female and 202 male, of which 342 had femoral neck fractures and 390 had trochanteric fractures.

Results: Of the total 732 patients, 346 patients (47.3%) had a 25(OH) vitamin D level of less than 10 ng/mL, 264 patients (36.1%) had scores of 10-19.9 ng/mL, 87 patients (11.9%) had scores of 20-29.9 ng/mL, and 35 patients (4.8%) had a level higher than 30 ng/mL. Vitamin D deficiency (less than 20 ng/mL) was present in 610 patients (83.3%), insufficiency (20-29.9 ng/mL) was found in 87 patients (11.9%), and 35 patients (4.8%) had normal vitamin D levels. The differences in vitamin D concentration based on season and fracture type were statistically significant.

Conclusion: Vitamin D deficiency and inadequacy were high in patients with low-energy hip fractures, with only 4.9% of patients had normal vitamin D levels. These findings suggest that efforts should be made to maintain proper vitamin D concentration.

Keywords: Hip fractures; Low energy; Vitamin D.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST: The authors declare that there is no potential conflict of interest relevant to this article.

Figures

Fig. 1
Fig. 1. Distribution of 732 patients according to level of vitamin D.
Fig. 2
Fig. 2. Distribution of patients according to vitamin D level by sex.
Fig. 3
Fig. 3. Distribution of patients according to vitamin D level by age.
Fig. 4
Fig. 4. Distribution of patients according to vitamin D level by season.
Fig. 5
Fig. 5. Distribution of patients according to vitamin D level by type of fracture.
Fig. 6
Fig. 6. Distribution of patients according to vitamin D level by preinjury ambulation.
Fig. 7
Fig. 7. Distribution of patients according to vitamin D level by residence.
See this image and copyright information in PMC

References

    1. Hill KM, Jonnalagadda SS, Albertson AM, Joshi NA, Weaver CM. Top food sources contributing to vitamin D intake and the association of ready-to-eat cereal and breakfast consumption habits to vitamin D intake in Canadians and United States Americans. J Food Sci. 2012;77:H170–H175. - PubMed
    1. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266–281. - PubMed
    1. Mithal A, Wahl DA, Bonjour JP, et al. Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int. 2009;20:1807–1820. - PubMed
    1. Cashman KD, Dowling KG, Škrabáková Z, et al. Vitamin D deficiency in Europe: pandemic? Am J Clin Nutr. 2016;103:1033–1044. - PMC - PubMed
    1. Ganji V, Zhang X, Tangpricha V. Serum 25-hydroxyvitamin D concentrations and prevalence estimates of hypovitaminosis D in the US population based on assay-adjusted data. J Nutr. 2012;142:498–507. - PubMed

LinkOut - more resources