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. 2020 Nov 19;133(24):2998-3000.
doi: 10.1097/CM9.0000000000001232.

Time to relapse after treatment withdrawal for different biologics used to treat plaque psoriasis

Affiliations

Time to relapse after treatment withdrawal for different biologics used to treat plaque psoriasis

Xiao-Yu Wang et al. Chin Med J (Engl). .
No abstract available

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Comparison of the median time to relapse among different biologics. (A) Head-to-head comparison of time to relapse (PGA ≥ 3) between etanercept and ustekinumab (left); head-to-head comparison of time to relapse (initiation of new systemic treatment) between secukinumab and guselkumab (right). (B) Time to relapse (loss of PASI 50) in individual studies. (C) Time to relapse (PGA ≥ 3) in individual studies. IL: Interleukin; PASI: Psoriasis Area and Severity Index; PGA: Physician's Global Assessment score; TNF: Tumor necrosis factor.

References

    1. Gordon KB, Gottlieb AB, Leonardi CL, Elewski BE, Wang A, Jahreis A, et al. Clinical response in psoriasis patients discontinued from and then reinitiated on etanercept therapy. J Dermatolog Treat 2006; 17:9–17. doi: 10.1080/09546630500472838. - PubMed
    1. Bellinato F, Girolomoni G, Gisondi P. Relapse of psoriasis in patients who asked to discontinue etanercept after achieving a stable clinical remission. Br J Dermatol 2019; 181:1319–1320. doi: 10.1111/bjd.18225. - PubMed
    1. Efficacy and safety of infliximab in long-term treatment of plaque-type psoriasis: A comparative retrospective study on two different (continuous vs. relapse related) regimens. J Am Acad Dermatol 2007; 56:B190.doi: 10.1016/j.jaad.2006.10.866.
    1. Papp K, Crowley J, Ortonne JP, Leu J, Okun M, Gupta SR, et al. Adalimumab for moderate to severe chronic plaque psoriasis: efficacy and safety of retreatment and disease recurrence following withdrawal from therapy. Br J Dermatol 2011; 164:434–441. doi: 10.1111/j.1365-2133.2010.10139.x. - PubMed
    1. Griffiths CE, Strober BE, van de Kerkhof P, Ho V, Fidelus-Gort R, Yeilding N, et al. Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis. N Engl J Med 2010; 362:118–128. doi: 10.1056/NEJMoa0810652. - PubMed