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Case Reports
. 2021:26:100263.
doi: 10.1016/j.ctarc.2020.100263. Epub 2020 Dec 10.

Regorafenib in glioblastoma recurrence: A case report

Beatrice Detti  1 , Silvia Scoccianti  2 , Sara Lucidi  2 , Virginia Maragna  2 , Maria Ausilia Teriaca  2 , Michele Ganovelli  2 , Isacco Desideri  2 , Victoria Lorenzetti  2 , Erika Scoccimarro  2 , Daniela Greto  2 , Lorenzo Livi  2
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Free article
Case Reports

Regorafenib in glioblastoma recurrence: A case report

Beatrice Detti et al. Cancer Treat Res Commun. 2021.
Free article

Abstract

GBM (glioblastoma multiforme) is the most common and aggressive brain tumor. To date, treatment options for glioblastoma recurrence are lacking. Recently, REGOMA trial showed the superiority of regorafenib to lomustine in patients with first glioblastoma recurrence. We report an excellent response to three months treatment with regorafenib, in a patient who presented a rapid progression after the end of post operative radio-chemotherapy and after only one cycle of adjuvant TMZ (Temozolomide).

Keywords: Glioblastoma recurrent; Malignant glioma; Regorafenib.

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