Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Oct 30;50(5):308-312.
doi: 10.4274/tjo.galenos.2020.94580.

Unintentional Staining of the Anterior Vitreous with Trypan Blue During Cataract Surgery

Özcan Rasim Kayıkçıoğlu  1 , Hüseyin Mayalı  1 , Suzan Doğruya  2 , Şenay Alp  3 , Aydın Alper Yılmazlar  4 , Emin Kurt  1
Affiliations
Case Reports

Unintentional Staining of the Anterior Vitreous with Trypan Blue During Cataract Surgery

Özcan Rasim Kayıkçıoğlu et al. Turk J Ophthalmol. .

Abstract

During phacoemulsification and intraocular lens (IOL) implantation surgery, the trypan blue dye used to stain the anterior capsule passed into vitreous cavity and stained the anterior capsule and anterior vitreous in 6 patients. There was history of trauma in 2 patients, uveitis in 1 patient, mature cataract in 1 patient, and no risk factors in the other patients. IOL was implanted in-the-bag without problem in 5 patients. In the patient with iris and zonular defects due to trauma, a sutured IOL was implanted in the same session. The migration of trypan blue into the vitreous cavity through damaged or intact lens zonules is a rare but important complication that makes subsequent surgical steps substantially more difficult.

Keywords: Trypan blue; phacoemulsification; vitreous.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
Posterior synechia, small pupil, and cataract reflex are observed in the peroperative initial appearance of our uveitic patient (patient 1)
Figure 2
Figure 2
Disappearance of the fundus reflex is observed during phacoemulsification with iris retractors
Figure 3
Figure 3
Intraocular lens placement (a) and appearance at the end of the operation (b)
Figure 4
Figure 4
Trypan blue staining of the posterior capsule and anterior vitreous is observed (patient 2
Figure 5
Figure 5
Ultrasound biomicroscopy reveals iris and zonular defects and lens opacity (patient 5). The red arrow indicates the area of zonular damage
See this image and copyright information in PMC

Comment in

Similar articles

See all similar articles

Cited by

References

    1. Jacobs DS, Cox TA, Wagoner MD, Ariyasu RG, Karp CL; American Academy of Ophthalmology; Ophthalmic Technology Assessment Committee Anterior Segment Panel. Capsule staining as an adjunct to cataract surgery: a report from the American Academy of Ophthalmology. Ophthalmology. 2006;113:707–713. - PubMed
    1. Sharma N, Bhartiya P, Sinha R, Vajpayee RB. Trypan blue assisted phacoemulsification by residents in training. Clin Exp Ophthalmol. 2002;30:386–387. - PubMed
    1. Bacsal KME, Chee SP. Trypan blue-associated retinal toxicity post complicated cataract surgery. Eye (Lond). 2006;20:1310–1311. - PubMed
    1. Chowdhury PK, Raj SM, Vasavada AR. Inadvertent staining of the vitreous with trypan blue. J Cataract Refract Surg. 2004;30:274–276. - PubMed
    1. Gaur A, Kayarkar VV. Inadvertent vitreous staining. J Cataract Refract Surg. 2005;31:649. - PubMed

Publication types

LinkOut - more resources