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. 2020 Dec 18;13(12):1922-1927.
doi: 10.18240/ijo.2020.12.12. eCollection 2020.

Study of corneal biomechanical properties in patients with childhood glaucoma

Sara Garcia Caride  1 , Lucia Perucho González  1 , Federico Sáenz Francés  1 , Julián García Feijoo  1
Affiliations

Study of corneal biomechanical properties in patients with childhood glaucoma

Sara Garcia Caride et al. Int J Ophthalmol. .

Abstract

Aim: To study of corneal biomechanical properties and intraocular pressure (IOP) measured with Corvis Scheimpflug Technology (ST) in patients with childhood glaucoma (CG).

Methods: Cross-sectional study in which 89 eyes were included 56 of them with CG. Only one eye per patient was included. The following variables were obtained from the clinical history and the ophthalmological examination: age, sex, IOP, number of surgeries, and the cup/disc ratio (CDR). The following parameters were recorded using Corvis ST: corrected by biomechanics IOP (bIOP), not corrected IOP (nctIOP), central corneal thickness (CCT), maximum concavity [radius, peak distance (PD) and deformation amplitude], applanation 1 and 2 (length and velocity). The mean age was 23±14.55 and 33±19.5 years old for the control group and CG group, respectively. Totally 36 were males and 53 were females. In the CG group, 7 patients were controlled only with medical treatment. Sixteen had at least one previous goniotomy, 19 had at least one trabeculectomy, and 11 had an Ahmed implant.

Results: A significant and positive intraclass correlation coefficient was found between Goldman IOP and the IOP measured by Corvis in both groups. No differences were found between the IOP measured with Corvis and Goldman using a student t-test. Regarding biomechanical parameters, there were differences in the applanation length 2 (A-L2), in the applanation velocity 2 (A-V2) and in the PD. By sex, only the applanation length 1 (A-L1) was found to be different in control group. A positive and significant Pearson correlation was found between CDR and the A-L1.

Conclusion: Corneal biomechanical properties have shown differences between CG and healthy subjects and also between men and women.

Keywords: Corvis Scheimpflug Technology; biomechanical properties; childhood glaucoma.

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Figures

Figure 1
Figure 1. Varieties of childhood glaucoma
SW: Sturge Weber Syndrome; JIA: Juvenile idiopathic arthritis; PCG: Primary congenital glaucoma.
See this image and copyright information in PMC

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