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Comment
. 2021 Feb;26(2):e347-e349.
doi: 10.1002/onco.13647. Epub 2021 Jan 9.

Metastatic Mediastinal Germ-Cell Tumor and Concurrent COVID-19: When Chemotherapy Is Not Deferrable

Paolo Pedrazzoli  1   2 , David Rondonotti  3 , Carlo Cattrini  3   4 , Simona Secondino  1 , Paolo Ravanini  5 , Antonio Piralla  6 , Pier Paolo Sainaghi  7 , Diego Brustia  8 , Cristina Bozzola  9 , Marisa Gariglio  10 , Christian Cossandi  11 , Giovanni Rosti  1 , Alessandra Gennari  3
Affiliations
Comment

Metastatic Mediastinal Germ-Cell Tumor and Concurrent COVID-19: When Chemotherapy Is Not Deferrable

Paolo Pedrazzoli et al. Oncologist. 2021 Feb.

Abstract

This letter to the editor describes the case of a patient with mediastinal germ cell tumor who developed COVID‐19 at the end of the first cycle of chemotherapy and continues the discussion on whether it is best to continue or delay administration of chemotherapy with an active COVID‐19 infection.

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Figures

Figure 1
Figure 1
Laboratory parameters at diagnosis and during treatment.Abbreviations: AFP, alpha‐fetoprotein; AU, arbitrary units; Ct, cycle threshold; IgG, immunoglobulin G; N, negative; P, positive; PBSC, peripheral blood stem cells; VIP, etoposide, ifosfamide, cisplatin.
Figure 2
Figure 2
Radiological findings. Computed tomography (CT) scan showing the mediastinal mass at baseline (A) and after two cycles of chemotherapy (B); CT scan performed after two cycles of chemotherapy showing interstitial pneumonia (C, D).
See this image and copyright information in PMC

Comment in

  • In Reply.
    Nappi L, Ottaviano M, Rescigno P, Messina C, Palmieri G. Nappi L, et al. Oncologist. 2021 Feb;26(2):e350. doi: 10.1002/onco.13651. Epub 2021 Jan 9. Oncologist. 2021. PMID: 33350011 Free PMC article.

Comment on

  • Management of Germ Cell Tumors During the Outbreak of the Novel Coronavirus Disease-19 Pandemic: A Survey of International Expertise Centers.
    Nappi L, Ottaviano M, Rescigno P, Tortora M, Banna GL, Baciarello G, Basso U, Canil C, Cavo A, Cossu Rocca M, Czaykowski P, De Giorgi U, Garcia Del Muro X, Di Napoli M, Fornarini G, Gietema JA, Heng DYC, Hotte SJ, Kollmannsberger C, Maruzzo M, Messina C, Morelli F, Mulder S, Nichols C, Nolè F, Oing C, Sava T, Secondino S, Simone G, Soulieres D, Vincenzi B, Zucali PA, De Placido S, Palmieri G; Italian Germ Cell Cancer Group (IGG); ERN-EURACAN Domain G3; Genitourinary Medical Oncologists of Canada (GUMOC). Nappi L, et al. Oncologist. 2020 Oct;25(10):e1509-e1515. doi: 10.1634/theoncologist.2020-0420. Epub 2020 Sep 18. Oncologist. 2020. PMID: 32735386 Free PMC article.

References

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