Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Dec 21:9:e64587.
doi: 10.7554/eLife.64587.

Muscle signals to the rescue

Affiliations

Muscle signals to the rescue

Arely V Diaz et al. Elife. .

Abstract

The skeletal muscle of fruit flies communicates with other organs to prevent the accumulation of too much fat and to protect adults against obesity.

Keywords: D. melanogaster; PDGF; VEGF; genetics; genomics; hepatocyte; mTOR; myokine; obesity.

PubMed Disclaimer

Conflict of interest statement

AD, TR No competing interests declared

Comment on

  • doi: 10.7554/eLife.56969

References

    1. Baker KD, Thummel CS. Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila. Cell Metabolism. 2007;6:257–266. doi: 10.1016/j.cmet.2007.09.002. - DOI - PMC - PubMed
    1. Benatti FB, Pedersen BK. Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation. Nature Reviews Rheumatology. 2014;11:86–97. doi: 10.1038/nrrheum.2014.193. - DOI - PubMed
    1. Doane WW. Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. I. Adult morphology, longevity, egg production, and egg lethality. Journal of Experimental Zoology. 1960;145:1–21. doi: 10.1002/jez.1401450102. - DOI - PubMed
    1. Eckel J. Myokines in metabolic homeostasis and diabetes. Diabetologia. 2019;62:1523–1528. doi: 10.1007/s00125-019-4927-9. - DOI - PubMed
    1. Fisher FM, Maratos-Flier E. Understanding the physiology of FGF21. Annual Review of Physiology. 2015;78:223–241. doi: 10.1146/annurev-physiol-021115-105339. - DOI - PubMed

MeSH terms

LinkOut - more resources