Osteoporosis and Fragility in Elderly Patients
- PMID: 33347225
- Bookshelf ID: NBK565578
- DOI: 10.1007/978-3-030-48126-1_3
Osteoporosis and Fragility in Elderly Patients
Excerpt
Osteoporosis is a systemic bone disease affecting numerous people all over the world, causing fragility fractures, especially among the elderly. In order to reach a complete diagnosis before a fragility fracture occurs, it is necessary, according to the main international guidelines, to perform a dual X-ray absorptiometry (DXA) to evaluate bone mineral density (BMD), an X-ray of the dorsal and lumbar spine to investigate the presence of asymptomatic vertebral fractures, laboratory tests to exclude secondary forms of osteoporosis, and draw up an accurate medical history, since several risk factors may be involved. The general management of this pathology includes prevention of further falls as well as the administration of calcium, vitamin D and protein supplements. Many drugs that permit a customised strategy—fundamental to improving treatment-adherence rates, frequently low in elderly patients—are available for the pharmacological treatment of this pathology.
Copyright 2021, The Author(s).
Sections
- 3.1. Definition
- 3.2. Epidemiology
- 3.3. The Anatomy of Bone
- 3.4. The Physiology of Bone
- 3.5. Pathogenesis
- 3.6. Risk Factors for Fragility Fractures
- 3.7. Diagnosis
- 3.8. Management of Osteoporosis
- 3.9. The Importance of Vitamin D, Calcium and Protein Intake
- 3.10. Therapeutic Adherence in Osteoporosis and the Role of Health Professionals
- References
References
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- Adami S, Bertoldo F, Brandi ML, Cepollaro C, Filipponi P, Fiore E, Frediani B, Giannini S et al (2009) Guidelines for the diagnosis, prevention and treatment of osteoporosis. Reumatismo 61:260–284 - PubMed
-
- Kanis J, Borgstrom F, De Leat C, Johansson H, Johnell O, Jonsson B, Odea A, Zethraeus N, Pfleger B, Khaltaev N et al (2005) Assessment of fracture risk. Osteoporos Int 16:581–589 - PubMed
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- Strom O, Borgstrom F, Kanis J, Compston J, Cooper C, McCloskey E, Jonsson B (2011) Osteoporosis: burden, healthcare provision and opportunities in the EU. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos 6:59–155 - PubMed
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- Kanis J, Compston J, Cooper C et al (2012) The burden of fractures in the European Union in 2010. Osteoporos Int 23:S57
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