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. 2020 Dec 24;99(52):e23526.
doi: 10.1097/MD.0000000000023526.

The effectiveness of a WeChat-based multimodal nursing program for women with breast cancer: A randomized controlled trial protocol

Na Zhao  1 , Fang Yin, Xiaofang Wu, Yuxia Zhong
Affiliations

The effectiveness of a WeChat-based multimodal nursing program for women with breast cancer: A randomized controlled trial protocol

Na Zhao et al. Medicine (Baltimore). .

Expression of concern in

  • Expression of Concern: Study Protocols.
    [No authors listed] [No authors listed] Medicine (Baltimore). 2025 Nov 7;104(45):e46330. doi: 10.1097/MD.0000000000046330. Medicine (Baltimore). 2025. PMID: 41204616 Free PMC article. No abstract available.

Abstract

Background:: Breast cancer is one of the most familiar malignant tumor all over the world in women. The main treatment for the early breast cancer is surgery accompanied by the adjuvant therapy. Nevertheless, these treatments can lead to adverse reactions including sleep disturbances, fatigue, and pain. For our research, the objective is to assess the therapeutic effect of nursing program based on WeChat for the female breast cancer.

Methods:: This is a randomized controlled research, and it will be carried out from November 2020 to May 2021, which was granted via the Ethics Committee of the Second Affiliated Hospital of Hainan Medical University (LW2020056). In this study, patients meeting the following criteria will be included:

  1. (1)

    patients aged 18 or older,

  2. (2)

    stage I to III disease,

  3. (3)

    patients newly diagnosed with the breast cancer, and

  4. (4)

    patients undergoing surgery accompanied by adjuvant therapy.

And patients with

  1. (1)

    mental or cognitive disorders and

  2. (2)

    other malignancies will be excluded.

In intervention group, the patients are given multi-mode nursing program based on WeChat and routine nursing. In control group, patients are given routine nursing, involving vital signs monitoring, the education of health, the monitoring of postoperative complications, as well as postoperative drainage tube nursing. The main outcomes are the change of Functional Assessment of Cancer Therapy-Breast version 4.0 (FACT-Bv4.0) score. While the secondary result is the numerical rating scale (NRS).

Results:: Table 1 shows the clinical results between study group and control group.

Conclusion:: This paper has guided nurses to develop an evidence-based protocol to improve patient care for postoperative women with breast cancer.

Trial registration:: This study protocol was registered in Research Registry (researchregistry6180).

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

References

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