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Case Reports
. 2020 Dec 7:2020:8858378.
doi: 10.1155/2020/8858378. eCollection 2020.

Ocrelizumab-Induced Severe Colitis

Hsing Hwa Lee  1 , Naveen Sritharan  1 , Daniel Bermingham  2 , Gabriela Strey  1
Affiliations
Case Reports

Ocrelizumab-Induced Severe Colitis

Hsing Hwa Lee et al. Case Rep Gastrointest Med. .

Abstract

We report a case of severe ocrelizumab (anti-CD20 monoclonal antibody) induced colitis in a 43-year-old woman with multiple sclerosis leading to total colectomy after failing medical therapy. Histology of the colectomy was consistent with medication-induced colitis.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Abdomen X-ray showing thumbprinting sign.
Figure 2
Figure 2
Distal sigmoid colon showing severe colitis.
Figure 3
Figure 3
Midsigmoid colon showing extension of the severe colitis to the midsigmoid region.
See this image and copyright information in PMC

References

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