Turning on ILC2s: diet control
- PMID: 33354805
- DOI: 10.1111/imcb.12429
Turning on ILC2s: diet control
Abstract
New research by Fali and colleagues shows that peroxisome proliferator-activated receptor gamma is a central metabolic regulator of group 2 innate lymphoid cells, controlling the functional activation of these potent innate immune initiators in lung and adipose tissue.
© 2020 Australian and New Zealand Society for Immunology, Inc.
Comment on
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Metabolic regulation by PPARγ is required for IL-33-mediated activation of ILC2s in lung and adipose tissue.Mucosal Immunol. 2021 May;14(3):585-593. doi: 10.1038/s41385-020-00351-w. Epub 2020 Oct 26. Mucosal Immunol. 2021. PMID: 33106586
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