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Editorial
. 2021 Jan;41(1):266-268.
doi: 10.1161/ATVBAHA.120.315437. Epub 2020 Dec 23.

New Cellular Source of TF (Tissue Factor)-Positive Extracellular Vesicles in the Circulation

Silvio Antoniak  1   2 , Nigel Mackman  1   3
Affiliations
Editorial

New Cellular Source of TF (Tissue Factor)-Positive Extracellular Vesicles in the Circulation

Silvio Antoniak et al. Arterioscler Thromb Vasc Biol. 2021 Jan.
No abstract available

Keywords: Editorials; cytokine; fibroblast; monocyte; oxidative stress; tissue factor.

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Figures

Figure:
Figure:. Cellular source of tissue factor-positive extracellular vesicles in mice injected with 4-hydroxy-2-nonenal or lipopolysaccharide.
Injection of 4-hydroxy-2-nonenal (HNE) disrupts the endothelial barrier and allows the release of tissue factor (TF)-positive extracellular vesicles (EVs) from perivascular cells into the circulation. TF+EVs present in the circulation of mice injected with lipopolysaccharide (LPS) are derived from both perivascular cells and activated monocytes. Endotoxemic mice also express TF on activated endothelium.
See this image and copyright information in PMC

Comment on

References

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