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Comment
. 2021 Apr;100(2_suppl):186S-187S.
doi: 10.1177/0145561320982686. Epub 2020 Dec 23.

Xerostomia and Taste Alterations in COVID-19

Maria Natally Belchior Fontenele  1 , Marlus da Silva Pedrosa  2
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Free article
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Xerostomia and Taste Alterations in COVID-19

Maria Natally Belchior Fontenele et al. Ear Nose Throat J. 2021 Apr.
Free article

Abstract

A recent letter published in the Ear, Nose & Throat Journal called attention to the hypothesis that the xerostomia reported in patients with the Coronavirus Disease 2019 (COVID-19) occurs due to the neuroinvasive and neurotropism potential of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In fact, angiotensin-converting enzyme 2 (ACE-2), the main site of entry of SARS-CoV-2 into the cell, was found to be present in the ductal elements of salivary gland and several other tissues. However, some points are worth to be addressed.

Keywords: COVID-19; hyposalivation; salivary glands; taste disturbances.

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